Results 161 to 170 of about 7,797,679 (378)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Formulation of gliclazide using self-nano-emulsification technology [PDF]

, 2018
Self-nano-emulsifying drugs delivery systems present an effective drug delivery system for the formulation of a hydrophobic drug with poor water-solubility.
Abdel-Aziz, Farah, Ball, Patrick, Morrissey, Hana, Nugroho, Bambang Hernawan, Saepudin   +4 more
core  

PEG Branched Polymer for Functionalization of Nanomaterials with Ultralong Blood Circulation

, 2009
Nanomaterials have been actively pursued for biological and medical applications in recent years. Here, we report the synthesis of several new poly(ethylene glycol) grafted branched-polymers for functionalization of various nanomaterials including carbon
Adams M. L., Ashiuchi M., Bruchez M., Chan W. C. W., Chatterjee T., Chen R. J., Chen Z., Cheng Y., Cognet L., Dieckmann G. R., Dubertret B., Fan H. Y., Gao M. Y., Gerion D., Han G., Huff T. B., Ipe B. I., Jiang W., Kam N. W. S., Kam N. W. S., Kanaras A. G., Karajanagi S. S., Kogan M. J., Kryachko E. S., Lin Wang W. Z., Liu W. H., Liu Z., Liu Z., LizMarzan L. M., Markowitz M. A., Maubach G., Mulder W. J. M., Nakayama-Ratchford N., Nam J. M., Nath N., Numata M., Oyelere A. K., O’Connell M. J., Paciotti G. F., Parveen S., Pinaud F., Porta F., Richard C., Schultz S., Selvan S. T., Sinani V. A., Sinha N., Sohn B. H., Sonnichsen C., Thaxton C. S., Tong L., Wang D., Welsher K., Williams K. A., Xiaoming Sun Z. L., Yang S. T., Zhelev Z., Zheng M., Zheng M.   +58 more
core   +1 more source

Physicochemical stability of ternary admixtures of butorphanol, ketamine, and droperidol in polyolefin bags for patient-controlled analgesia use

Drug Design, Development and Therapy, 2016
Baoxia Fang,1 Linhai Wang,2 Junfeng Gu,3 Fuchao Chen,1 Xiao-ya Shi1 1Department of Pharmacy, Dongfeng Hospital, 2Department of Pharmacy, 3Department of Anesthesiology, Renmin Hospital, Hubei University of Medicine, Hubei, People’s Republic of
Fang BX, Wang LH, Gu JF, Chen FC, Shi XY
doaj  

Reference on the extended stability of injectable drugs for home care [PDF]

, 2000
Caryn M. Bing
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

High-throughput cassette assay for drug stability measurement in plasma using direct HPLC-MS/MS [PDF]

, 2003
Gangfeng Wang, Yunsheng Hsieh, Kui Cheng, Kwokei Ng, Walter A. Korfmacher   +4 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Daptomycin: a comparison of two intravenous formulations

Drug Design, Development and Therapy, 2018
Celeste Frankenfeld, Sachin Mittal, Yanira Melendez, Luke Mendez-Vigo, Kenneth C Lamp, Kaitlin N Keller, Shellie R Bertolami Merck & Co., Inc., Kenilworth, NJ, USA Abstract: Daptomycin is a cyclic lipopeptide antibacterial agent with potent ...
Frankenfeld C, Mittal S, Melendez Y, Mendez-Vigo L, Lamp KC, Keller KN, Bertolami SR   +6 more
doaj  

Temporal stability of the timeline followback interview for alcohol and drug use with psychiatric outpatients. [PDF]

, 2004
Kate B. Carey, Michael P. Carey, Stephen A. Maisto, James M. Henson   +3 more
openalex   +1 more source