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Application and Potential of Local Drug Delivery Systems for Antibacterial Treatment of Periodontitis. [PDF]
Int J Mol SciWang X, Wu F, Liu J, Hong X, Dong S.
europepmc +1 more source
Pharmaceutical Technology: Drug Stability
Journal of Pharmaceutical Sciences, 1990 openaire +1 more source
Limitations of Complement Activity Assays as Biomarkers for Ravulizumab Therapeutic Monitoring
Annals of Clinical and Translational Neurology, EarlyView.
Francesco Saccà, Ryan Pelto
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Supramolecularly stabilized diabetes drugs
Nature Biomedical Engineering, 2020The stabilization of co-administered insulin and pramlintide with cucurbit[7]uril-conjugated poly(ethylene glycol) in diabetic pigs enhances the overlap of their therapeutic windows.
Kim, Henriksen, Morten A, Karsdal
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Antiepileptic Drugs and Mood Stability
Clinical EEG and Neuroscience, 2007This paper will discuss different definitions of the term “mood stabilizer” and highlight in detail the antiepileptic drugs carbamazepine, valproate and lamotrigine with respect to their relative strengths in stabilizing mood in bipolar patients. These drugs are heterogeneous in their mechanisms of action and in their efficacy to stabilize patients ...
Benedikt, Amann +3 more
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Stability Challenges in Drug Discovery
Chemistry & Biodiversity, 2009AbstractStability is one of the most important properties of drug candidates. Instable compounds can lead to false positive high‐throughput screening (HTS) hits, incorrect bioassay results, erroneous structure–activity relationships (SAR), low oral bioavailability, drug withdrawal, toxic reactions from degradation products, and difficult formulation ...
Li, Di, Edward H, Kerns
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2020
This chapter evaluates drug stability, which is a vital aspect of drug development. The types of stability that will need to be examined are physical stability and chemical stability. In particular, at an early stage, it is important to determine the mechanism of any instability, the reaction kinetics involved in any instability, and the factors that ...
openaire +1 more source
This chapter evaluates drug stability, which is a vital aspect of drug development. The types of stability that will need to be examined are physical stability and chemical stability. In particular, at an early stage, it is important to determine the mechanism of any instability, the reaction kinetics involved in any instability, and the factors that ...
openaire +1 more source