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Statistical analysis of drug stability
Computers & Industrial Engineering, 1999Regression models are used to express the behavior of label claim of a pharmaceutical product through time. A homogeneity test has been introduced to derive a reliable model for estimating the expiration date. The fitted models to the stability data can be used to generate a random sample for modeling the drug degradation time.
Luis A. Olivares+1 more
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[Human thrombin: drug stability and stabilization].
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 2007Stabilization of enzymes is a key factor when using biocatalysis in practice. Each enzyme stability depends both on the structure of its molecule and on the effect of various environmental factors, thus, one of the methods of the enzyme stability preservation is the formation of optimal macromedium.
M V, Kolodzeĭskaia+2 more
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Maillard Reaction and Drug Stability
2005Summary The great majority of drugs have amine functionality. These drugs when mixed with reducing sugars or other carbonyl containing pharmaceutical adjuvants often produce extensive mottling or discoloration, (“Maillard browning”), of the final dosage form over time.
Vijay Kumar, Gilbert S. Banker
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Stabilization and preformulation of anticancer drug—SarCNU
International Journal of Pharmaceutics, 2002The stability of SarCNU (NSC364432), 1-(2-chloroethyl)-3-sarcosinamide-1-nitrosourea in several pharmaceutically acceptable solvents was investigated by high pressure liquid chromatography (HPLC). The influences of light, ionic strength, pH, buffer concentration, and the following excipients: benzyl alcohol, ascorbic acid, sodium bisulfite, and ...
Nina Ni+2 more
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Stability of Drugs after Reconstitution [PDF]
R. David Anderson+2 more
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Stability of essential drugs in Sudan
The Lancet, 1991H. V. Hogerzeil+2 more
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Improving the stability of anticancer drugs
Journal of Oncology Pharmacy Practice, 2013Stephen Barton+2 more
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