Results 71 to 80 of about 324,046 (262)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Annals of Mechnikov's Institute, 2021 Introduction. Currently, there are no means for the treatment of dermatological diseases in the domestic pharmaceutical market with the simultaneous correction and maintenance of the skin microbiome.
Alina Solovyova, Olga Kaliuzhnaia
doaj
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
National Journal of Community MedicineBackground: Improper drug storage is immensely prevalent in households. A significant number of families do not follow prescribed practices for maintaining the safety and efficacy of medications.
Nancy L +4 more
doaj +1 more source
Potential Use of College of American Pathologists Accredited Biorepositories to Bridge Unmet Need for Medical Refrigeration Using Ultralow Temperature Storage for COVID-19 Vaccine or Drug Storage. [PDF]
Biopreserv Biobank, 2021 Kaushal S, Molinolo A.
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
JIIS: Jurnal Ilmiah Ibnu Sina, 2016 The storage management of drugs in hospitals must be good and true that the availability of pharmaceuticals is guaranteed in accordance with the needs of the hospital.
Nurul Qiyaam, Nur Furqoni, Hariati
doaj
Production and application of a portable anti-loss safety medicine box
Pakistan Journal of Pharmaceutical SciencesThe production and application of a portable anti-loss safety medicine box are explored to address high loss rate of anesthetic drugs in hospitals. This study aimed to develop and evaluate efficacy of portable anti-loss safety medicine box for anesthetic
Zhiguo Zhou +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source