Results 1 to 10 of about 4,654,627 (208)

Biopolymeric Nanogel as a Drug Delivery System for Doxorubicin—Improved Drug Stability and Enhanced Antineoplastic Activity in Skin Cancer Cells [PDF]

Pharmaceuticals
In this study, doxorubicin was loaded in a chitosan–albumin nanogel with the aim of improving its stability and exploring the potential of the system in the treatment of skin cancer. Infrared spectroscopy and X-ray diffraction confirmed the encapsulation
Lyubomira Radeva, Maya M. Zaharieva, Ivanka Spassova, Daniela Kovacheva, Ivanka Pencheva-El Tibi, Hristo Najdenski, Krassimira Yoncheva   +6 more
doaj   +2 more sources

A Nanoparticle-Based Strategy to Stabilize 5-Azacytidine and Preserve DNA Demethylation Activity in Human Cardiac Fibroblasts

Pharmaceutics
Background: 5-Azacytidine (5-Aza) is a clinically important DNMT inhibitor with the potential to modulate cardiac remodeling by epigenetically reprogramming human cardiac fibroblasts (HCFs).
Kantaporn Kheawfu, Chuda Chittasupho, Sudarshan Singh, Siriporn Okonogi, Narainrit Karuna   +4 more
doaj   +1 more source

Organizadores e cortadores de comprimidos: riscos e restrições ao uso Organizadores y cortadores de comprimidos: riesgos y restricciones del uso Pill organizers and pill cutters: risks and limitations

Revista de Saúde Pública, 2013
Com base em análise documental, foram discutidas e problematizadas as limitações associadas à utilização de organizadores e cortadores de comprimidos, como questão de saúde pública. Os organizadores destinados ao armazenamento e transporte de comprimidos
Caroline Ribeiro de Borja-Oliveira
doaj  

Drug–Phospholipid Co-Amorphous Formulations: The Role of Preparation Methods and Phospholipid Selection

Pharmaceutics
Background/Objectives: This study aims to broaden the knowledge on co-amorphous phospholipid systems (CAPSs) by exploring the formation of CAPSs with a broader range of poorly water-soluble drugs, celecoxib (CCX), furosemide (FUR), nilotinib (NIL), and ...
Keyoomars Khorami, Sam Darestani Farahani, Anette Müllertz, Thomas Rades   +3 more
doaj   +1 more source

Beyond use date of drugs [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2018
Context: There are standards that allow establishing the microbiological and physicochemical stability of a medicine; however, beyond use date of drugs depends not only on these criteria, but also on individual institutional characteristics. The multiple
Laura M. Rendón, Sara Lopera, Naira Y. Valencia   +2 more
doaj  

Physicochemical and Microbiological Stability of a New Oral Clonidine Solution for Paediatric Use

Pharmaceutical Technology in Hospital Pharmacy, 2018
As many drugs are unavailable for paediatric use, hospital pharmacies are often required to develop suitable formulations themselves. Clonidine is commonly used in paediatrics (in severe hypertension, in opiate withdrawal syndrome, in tics and Gilles de ...
Verlhac Camille, Lannoy Damien, Bourdon Florence, Titecat Marie, Frealle Emilie, Nassar Carole, Berneron Christophe, Odou Pascal   +7 more
doaj   +1 more source

DETERMINATION OF THE STABILITY OF A LOCAL ANESTHETIC BROMOKAIN TRANSDERMAL THERAPEUTIC SYSTEM

Вестник трансплантологии и искусственных органов, 2014
Aim. To study the stability of biocompatible microemulsion composition-based bromokain transdermal therapeutic systems (TTS) in order to confi rm the original shelf life and to identify the most appropriate TTS composition for storage.Materials and ...
V. A. Ryzhikova, E. G. Kuznetsova, V. Yu. Belov, L. A. Salomatina, V. I. Sevastianov   +4 more
doaj   +1 more source

Daptomycin: a comparison of two intravenous formulations

Drug Design, Development and Therapy, 2018
Celeste Frankenfeld, Sachin Mittal, Yanira Melendez, Luke Mendez-Vigo, Kenneth C Lamp, Kaitlin N Keller, Shellie R Bertolami Merck & Co., Inc., Kenilworth, NJ, USA Abstract: Daptomycin is a cyclic lipopeptide antibacterial agent with potent ...
Frankenfeld C, Mittal S, Melendez Y, Mendez-Vigo L, Lamp KC, Keller KN, Bertolami SR   +6 more
doaj  

Eudragit RS100 nanoparticles for sustained release of Cefpodoxime Proxetil: preparation, pharmaceutical characterization, and in-vitro drug release studies [PDF]

Nanomedicine Journal
Objective(s): The primary objective of this study was to develop a sustained-release formulation of cefpodoxime proxetil (CP) using the polymer Eudragit RS 100 (ERS100).Materials and Methods: Pluronic F127 (PF127) was incorporated as an amphiphilic ...
Jaya Verma, Saurabh Shekhar, Monika ,, Vikas Jhawat, Mahima Chauhan, Sonali, ,, Rahul Pratap Singh   +6 more
doaj   +1 more source

Criteria for Judging the Quality of a Publication on Physicochemical Stability of Ready to Use Injectable Drugs

Pharmaceutical Technology in Hospital Pharmacy, 2017
In hospitals, a major part of the drugs is administered via the intravenous route. When one wants to evaluate or know the stability of a drug in solution, it is necessary to know several physico-chemical parameters.
Hecq Jean-Daniel, Bihin Benoit, Jamart Jacques, Galanti Laurence   +3 more
doaj   +1 more source