Pharmaceutics, 2023 Background: Stability study of a 10 mg/mL injectable cisatracurium solution stored refrigerated in amber glass ampoules for 18 months (M18). Methods: 4000 ampoules were aseptically compounded using European Pharmacopoeia (EP)-grade cisatracurium besylate,
Marine Roche +7 more
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Challenges of Dissolution Methods Development for Soft Gelatin Capsules
Pharmaceutics, 2021 Recently, the development of soft gelatin capsules (SGCs) dosage forms has attracted a great deal of interest in the oral delivery of poorly water-soluble drugs.
Festo Damian +4 more
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Molecules, 2021 The evolution of different antimicrobial drugs in terrestrial, microgravity and hypergravity conditions is presented within this review, in connection with their implementation during human space exploration.
Ágota Simon +3 more
doaj +1 more source
Novel Findings about Double-Loaded Curcumin-in-HPβcyclodextrin-in Liposomes: Effects on the Lipid Bilayer and Drug Release [PDF]
, 2018 In this study, the encapsulation of curcumin (Cur) in “drug-in-cyclodextrin-in-liposomes (DCL)” by following the double-loading technique (DL) was proposed, giving rise to DCL–DL.
Fernández Romero, Ana María +4 more
core +2 more sources
Acrylamides with hydrolytically labile carbonate ester side chains as versatile building blocks for well-defined block copolymer micelles via RAFT polymerization [PDF]
, 2017 En route towards improved delivery systems for targeted chemotherapy, we propose a straightforward approach for the hydrophobic modification of the acrylamide N-(2-Hydroxyethyl) acrylamide (HEAm).
De Geest, Bruno +8 more
core +1 more source
Pharmaceutics, 2022 Janus kinase (JAK) inhibitors, such as tofacitinib (Xeljanz) and filgotinib (Jyseleca), have been approved for treatment of ulcerative colitis with several other JAK inhibitors in late-stage clinical trials for inflammatory bowel disease (IBD).
Vipul Yadav +16 more
doaj +1 more source
In vitro and in vivo screening for novel essential cell-envelope proteins in Pseudomonas aeruginosa [PDF]
, 2015 The Gram-negative bacterium Pseudomonas aeruginosa represents a prototype of multi-drug resistant opportunistic pathogens for which novel therapeutic options are urgently required.
Bragonzi, Alessandra +5 more
core +1 more source
Jornal de Pediatria, 2009 OBJETIVO: Verificar o potencial hidrogeniônico (pH) de soluções de cloridrato de dobutamina sob condições ambientais que mimetizam unidades de cuidados intensivos neonatais.
Lidiane L. Reis +2 more
doaj +1 more source
Review of binary, ternary and quaternary mixtures for induction and maintenance of opioid free anesthesia [PDF]
Farmacia Hospitalaria, 2021 Objective: To describe and organize the current information available on binary, ternary and/or quaternary mixtures used in opioid-free anesthesia (OFA), as well as their physicochemical stability, in order to facilitate its correct administration ...
Beatriz Tauste-Hernández +3 more
doaj +1 more source
Hydrogen-bonded multilayer thin films and capsules based on poly(2-n-propyl-2-oxazoline) and tannic acid : investigation on intermolecular forces, stability, and permeability [PDF]
, 2019 In recent years, hydrogen-bonded multilayer thin films and capsules based on neutral and nontoxic building blocks have been receiving interest for the design of stimuli-responsive drug delivery systems and for the preparation of thin-film coatings ...
Hoogenboom, Richard +5 more
core +1 more source