Results 151 to 160 of about 4,420,912 (284)

Bioinspired Adaptive Surfaces for Intelligent Liquid Manipulation: Progressing From Passive and Active to Hybrid Strategies

Advanced Materials, EarlyView.
This review examines passive, active, and hybrid liquid manipulation strategies, highlighting hybrid approaches as an emerging route to reconcile energy efficiency with adaptive control. By actively reconstructing passive surfaces to store programmable interfacial energy, hybrid systems enable flexible yet low‐power liquid transport, with perspectives ...
Jiaqi Miao, Yiyuan Zhang, Liqiu Wang, Alan C. H. Tsang   +3 more
wiley   +1 more source

From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates

Advanced Materials, EarlyView.
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot, Sebastian Jung, Sébastien Harlepp, Alexandre Detappe   +3 more
wiley   +1 more source

Isobolographic Analysis of the Interaction Between Remimazolam and Etomidate in General Anesthesia Induction: A Prospective, Sequential Allocation Study Based on the Dixon Up-and-Down Method. [PDF]

Drug Des Devel Ther
Yue W, Huang J, Wang Q, Zheng F, Yin P, Jin Y, Wang Y, Zhang L.   +7 more
europepmc   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Enhanced Antitumor Response in Breast Cancer via Parthanatos Activation Mediated by the Synergistic Effect of Etoposide and Resveratrol. [PDF]

Curr Issues Mol Biol
Taghavi Pourianazar N, Abdullah N.
europepmc   +1 more source

Resistance of herpes simplex virus to 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine: physical mapping of drug synergism within the viral DNA polymerase locus.

Proceedings of the National Academy of Sciences of the United States of America, 1984
C. Crumpacker, P. Kowalsky, S. Oliver, L. Schnipper, A. Field   +4 more
semanticscholar   +1 more source

Multifunctional Wound Dressings: Melt Electrowritten Scaffolds Combined With Phytotherapeutic Composite Hydrogels

Advanced Materials Interfaces, EarlyView.
ABSTRACT The increasing prevalence of impaired wounds, caused mainly by diabetes or aging, alongside the growing number of bacterial infections, indicates the need for alternative tissue engineering solutions. In this study, we developed novel melt electrowritten (MEW) polycaprolactone (PCL) scaffolds incorporated with an alginate (Alg)–gelatin (Gel ...
Andrada‐Ioana Damian‐Buda, Aldo Roberto Boccaccini, Irem Unalan   +2 more
wiley   +1 more source

Conocarpan and Eupomatenoid-6 as Natural Prototypes for Antituberculosis Compounds. [PDF]

Int J Microbiol
Silva LL, Ramos AVG, Baldoqui DC, de Souza Santos NC, Siqueira VLD, Caleffi-Ferracioli KR, Cardoso RF, da Silva RZ, de Lima Scodro RB.   +8 more
europepmc   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source