Advanced Healthcare Materials, EarlyView.Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett +13 more
wiley +1 more source
Emerging Synergisms Between Drugs and Physiologically-Patterned Weak Magnetic Fields: Implications for Neuropharmacology and the Human Population in the Twenty-First Century [PDF]
, 2007 Paul D. Whissell, Michael A. Persinger
openalex +1 more source
Advanced Healthcare Materials, EarlyView.A magnetic microrobot fabricated by Spirulina platensis is proposed to accumulate in tumor regions and generate in situ high calcium concentration and sufficient oxygen. These characteristics of the microrobot present a strategy for triggering calcium overload therapy and chlorophyll‐mediated photodynamic therapy, and such combination resulted in a ...
Shuai Jiang +12 more
wiley +1 more source
Advantages and Challenges of Using Antimicrobial Peptides in Synergism with Antibiotics for Treating Multidrug-Resistant Bacteria. [PDF]
ACS Infect DisGonçalves RM +6 more
europepmc +1 more source
Methionine depletion with recombinant methioninase: In vitro and in vivo efficacy against neuroblastoma and its synergism with chemotherapeutic drugs [PDF]
, 2008 Jian Hu, Nai‐Kong V. Cheung
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Universal Hydrogel Carrier Enhances Bone Graft Success: Preclinical and Clinical Evaluation
Advanced Healthcare Materials, EarlyView.TX hydrogel improves the delivery of different types of particulate bone grafts, maintaining them at the implantation sites, and resulting in favorable bone regenerative outcomes. Abstract Orthopedic, maxillofacial, and complex dentoalveolar bone grafting procedures that require donor‐site bone harvesting can be associated with post‐surgical ...
Dax Calder +9 more
wiley +1 more source
A classification model to predict synergism/antagonism of cytotoxic mixtures using protein-drug docking scores [PDF]
, 2008 John C. Boik, Robert A. Newman
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Advanced Healthcare Materials, EarlyView.This study developed a biomimetic scaffold incorporating PDRN and melatonin to restore ovarian function in chemotherapy‐induced premature ovarian insufficiency, enhancing cell survival, folliculogenesis, and hormone normalization, while improving fertility rates and offspring in a mouse model, offering a promising strategy for ovarian function ...
Da‐Seul Kim +8 more
wiley +1 more source
Synergism between inhibitors of Aurora A and KIF11 overcomes KIF15‐dependent drug resistance [PDF]
, 2014 Hoi Tang +3 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.Ovarian cancer's high recurrence and therapy resistance demand new strategies. A high‐throughput drug screening pipeline using 3D spheroids, which showed poor concordance with 2D models, identified rapamycin as a promising candidate. In combination with cisplatin, rapamycin demonstrated significant in vitro and in vivo efficacy, highlighting the ...
Nazanin Karimnia +9 more
wiley +1 more source