Results 221 to 230 of about 10,148,101 (391)

Using pharmacogenomics to personalise drug therapy: which drugs, when and how. [PDF]

Aust Prescr
Stocker SL, Polasek TM.
europepmc   +1 more source

We can manage depression better with technology [PDF]

Provides a summary of the evidence for internet-delivered cognitive behaviour therapy, and looks at the three RACGP Handbook of Non-Drug Intervention (HANDI) recommendations for non-drug treatments for depression and arranged for the developers to ...
Gavin Andrews
core  

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Postexposure Antimicrobial Drug Therapy in Goats Infected with Burkholderia pseudomallei. [PDF]

Emerg Infect Dis
Bowen RA, Hartwig AE, Bosco-Lauth AM, Seixas JN, Ritter JM, Fair PS, Elrod MG, Weiner ZP, Stoddard RA, Vieira AR, Maison RM, Lawrence E, Sueper H, Barker M, Bower WA.   +14 more
europepmc   +1 more source

Therapy of leishmaniasis: Superior efficacies of liposome-encapsulated drugs

, 1978
Carl R. Alving, Edgar A. Steck, Willie L. Chapman, Virginia B. Waits, Larry D. Hendricks, Glenn M. Swartz, William L. Hanson   +6 more
openalex   +1 more source

A Representative Survey of M.S. Patients on Attitudes toward the Benefits and Risks of Drug Therapy [PDF]

Background: Although M.S. patients face significant trade-offs between risks and benefits of drug therapy, little is known of their attitudes toward these risks and benefits.
Calfee, John E.
core   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

Molecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan, Moshe Leitner, Amos Toren, Shoshana Paglin, Michal Yalon   +4 more
wiley   +1 more source

Fitness seascapes are necessary for realistic modeling of the evolutionary response to drug therapy. [PDF]

Sci Adv
King ES, Stacy AE, Weaver DT, Maltas J, Barker-Clarke R, Dolson E, Scott JG.   +6 more
europepmc   +1 more source

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

Molecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

New approaches to targeted drug therapy of intracranial tumors. [PDF]

Cell Death Discov
Beylerli O, Gareev I, Musaev E, Roumiantsev S, Chekhonin V, Ahmad A, Chao Y, Yang G.   +7 more
europepmc   +1 more source