Results 241 to 250 of about 2,964,728 (312)

From Data to Dose: Diversity in Therapeutic Drug Monitoring and Pharmacokinetics-Based Individualization of Drug Therapy. [PDF]

Pharmaceutics
Karvaly GB, Vásárhelyi B.
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Fitness seascapes are necessary for realistic modeling of the evolutionary response to drug therapy. [PDF]

Sci Adv
King ES, Stacy AE, Weaver DT, Maltas J, Barker-Clarke R, Dolson E, Scott JG.   +6 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Pharmacomicrobiomics: a new field contributing to optimizing drug therapy in Parkinson's disease. [PDF]

Gut Microbes
Zhang Y, Mo C, Ai P, He X, Xiao Q, Yang X.   +5 more
europepmc   +1 more source

Catheter ablation vs. anti-arrhythmic drug therapy for ventricular tachycardia in ischaemic heart disease: a meta-analysis of randomized controlled trials. [PDF]

Europace
Santoro F, Mugnai G, Perrotta L, Kovacs B, Dinshaw L, Del Castillo AM, Jungen C, Kurath-Koller S, Stojković S, Vandenberk B, Vernooy K.   +10 more
europepmc   +1 more source

Perceptions and Expectations of Pharmacist Interventions in Adverse Event Management During Drug Therapy for Metastatic Renal Cell Carcinoma: A Cross-Sectional Survey in Japan. [PDF]

Cancers (Basel)
Wako T, Kimura G, Fujii Y, Osawa T, Uchitomi Y, Honda K, Kondo M, Otani A, Mitsuda Y, Shinohara N.   +9 more
europepmc   +1 more source

Regulatory Mechanism and Drug Therapy of NLRP3 Inflammasome in Recurrent Pregnancy Loss: Research Status and Prospect. [PDF]

J Inflamm Res
Cui Y, Yang Y, Li Y, Zhang Y, Niu D, Feng X.   +5 more
europepmc   +1 more source

Practice pattern of aerosol drug therapy in ARDS patients: A secondary analysis of the Aero-in-ICU study. [PDF]

J Intensive Med
Singhal S, Saran S, Joshi K, Gurjar M, Rao PB, Sahoo JN, Dua R, Sahoo AK, Sharma A, Agarwal S, Sharma A, Ghosh PS, Kothari N, Deokar K, Mukherjee S, Sharma P, Sreedevi B, Sivaramakrishnan P, Singh U, Sundaram D, Agrawal A.   +20 more
europepmc   +1 more source