Drug tolerability versus drug safety
Journal of Dermatological Treatment, 2023 Drug tolerability and drug safety are sometimes used interchangeably, but they represent somewhat different concepts. This editorial examines the differences between drug tolerability and safety.
Stuti Prajapati +2 more
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Adverse Event Profiles of Antiseizure Medications and the Impact of Coadministration on Drug Tolerability in Adults with Epilepsy. [PDF]
CNS Drugs, 2023 Background Antiseizure medication (ASM) as monotherapy or in combination is the treatment of choice for most patients with epilepsy. Therefore, knowledge about the typical adverse events (AEs) for ASMs and other coadministered drugs (CDs) is essential ...
Willems LM +7 more
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Drug tolerability and reasons for discontinuation of seven biologics in elderly patients with rheumatoid arthritis -The ANSWER cohort study. [PDF]
PLoS One, 2019 Background The aim of this study is to evaluate the retention rates and reasons for discontinuation for seven biological disease-modifying antirheumatic drugs (bDMARDs) in a real-world setting of elderly patients (65 years of age or older) with ...
Ebina K +17 more
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Drug tolerability and reasons for discontinuation of seven biologics in 4466 treatment courses of rheumatoid arthritis-the ANSWER cohort study. [PDF]
Arthritis Res Ther, 2019 BackgroundThe aim of this study is to evaluate the retention rates and reasons for discontinuation for seven biological disease-modifying antirheumatic drugs (bDMARDs) in a real-world setting of patients with rheumatoid arthritis (RA).MethodsThis multi ...
Ebina K +17 more
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Sublingual Administration of Sildenafil Oro-dispersible Film: New Profiles of Drug Tolerability and Pharmacokinetics for PDE5 Inhibitors. [PDF]
Front Pharmacol, 2018 Objective: Type 5 phosphodiesterase inhibitors (PDE5i) are efficient drugs used for treatment of erectile dysfunction (ED); however, a large discontinuation rate due to major side effects is reported.
De Toni L +7 more
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Heliyon, 2023 Background: Achillea millefolium, known as Yarrow, is a medicinal plant in the Asteraceae family which is one of the oldest known botanicals used by humans and itis one of the most important medicinal plants in the pharmaceutical field.
Bahareh Farasati Far +2 more
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Beyond the hype: Antibody-Drug Conjugates are advancing faster than our clinical strategy. [PDF]
PLoS MedicineAntibody-drug conjugates are redefining treatment options in advanced breast cancer, demonstrating efficacy across all breast cancer subtypes. However, their rapid clinical expansion has resulted in several unresolved challenges, including the need for ...
Giulia Notini +3 more
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WITHDRAWN: Opioid switching to improve pain relief and drug tolerability. [PDF]
Cochrane Database Syst Rev, 2013 Quigley C.
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Effectiveness, safety and assessing the results of drug therapy in patients with epilepsy
Эпилепсия и пароксизмальные состояния, 2021 On June 26, 2021, a meeting of the experts of the Russian League Against Epilepsy (RLAE) was held, dedicated to the effectiveness, safety and assessing the results of drug therapy in patients with epilepsy.
article Editorial
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Клинический разбор в общей медицине, 2023 A meeting of the Central Federal District Neurologists-Epileptologists Expert Council dedicated to the issue of antiepileptic therapy in the CFD regions relative to global data and Russian guidelines was held on December 10, 2022.
N.A. Ermolenko +8 more
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