Results 131 to 140 of about 345,035 (349)
RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis
Advanced Science, EarlyView.Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao +28 more
wiley +1 more source
Advanced Science, EarlyView.By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao +11 more
wiley +1 more source
GLOMMING TO GLOOM: THE RAGING PERIL OF DRUG ABUSE AND TRAFFICKING IN NIGERIA
, 2022 Babatope Matthew Ajiboye
openalex +1 more source
Advanced Science, EarlyView.An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang +10 more
wiley +1 more source
Narco-productions in the historical memory debate in Colombia
RHS Revista Humanismo y SociedadColombia has been deeply impacted by drug trafficking, a phenomenon that has shaped its history and culture. This recurring theme has also been widely explored in the country’s audiovisual productions, drawing criticism for its pervasive presence ...
Jonatan David Arrieta Rojas
doaj +1 more source
Advanced Science, EarlyView.Chronic septic arthritis involves intracellular bacterial persistence and lipid‐immune crosstalk via the PGRN‐BMP lysosomal axis. A dual‐targeting nanoparticle system (NPs@PGRN) restores lysosomal bactericidal function, reduces bacterial burden, and reprograms macrophage immunity, offering a novel therapeutic strategy. ABSTRACT Chronic septic arthritis,
Congsun Li +12 more
wiley +1 more source
Causes Of Rising Drug Trafficking In India And Ways To Stop Drug Trafficking
International Journal For Multidisciplinary ResearchAbstract Drug trafficking is the worldwide practice of distributing drugs and other substances which are legally banned under narcotics and associated laws. It includes the cultivation, manufacture, distribution, and sale of controlled substances. In India, the use of drugs in society especially among the younger generation has increased in the past ...
Priyanka Singh -, Mohini Taneja -
openaire +1 more source
Interaction of Copper Trafficking Proteins with the Platinum Anticancer Drug Kiteplatin [PDF]
, 2021 Alessandra Barbanente +7 more
openalex +1 more source
Trafficking in Persons: U.S. Policy and Issues for Congress [PDF]
, 2012 [Excerpt] This report focuses on international and domestic human trafficking and U.S. policy responses, with particular emphasis on the TVPA and its subsequent reauthorizations.
Siskin, Alison, Wyler, Liana Sun
core +4 more sources
Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53
Advanced Science, EarlyView.NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore +20 more
wiley +1 more source