Results 111 to 120 of about 345,035 (349)
Advanced Healthcare Materials, EarlyView.ABSTRACT The ascent of novel alternative methods in drug development spotlights the dual needs for improved biological fidelity to in vivo, along with reproducibility, especially in regulatory applications. The need for pre‐clinical models of patient‐derived endometriosis lesions motivates the development of a vascularizable, completely synthetic ...
Lauren Pruett +7 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A two‐phase workflow (OFAT screening followed by central composite design) maps how processing variables tune PFCE‐PLGA nanoparticle size, dispersity, surface charge, loading, and 19F‐MRI signal. In situ, time‐resolved synchrotron SAXS tracks albumin‐corona growth on intact dispersions and reveals PFCE‐dependent adsorption pathways.
Joice Maria Joseph +11 more
wiley +1 more source
HUMAN TRAFFICKING: THE BAHRAIN EXPERIENCE [PDF]
Drug smuggling may top the list of the world’s most profitable and headline-grabbing illegal activities, but second to that —in a close tie with the illegal arms trade — is human trafficking, the recruitment or coercion of people who are held captive as ...
Ali Al JABAL
core
Advanced Healthcare Materials, EarlyView.Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni +13 more
wiley +1 more source
The EU Strategy for Central Asia says 'security'. Does this include Security Sector Reform? EUCAM Policy Brief No. 10, 12 November 2009 [PDF]
, 2009 Central Asia faces a broad range of security challenges. Due to the region's position at the crossroads between Russia, China and Afghanistan, Pakistan, Iran and the Caspian Sea it is confronted with a range of trans-national issues such as drug ...
Boonstra, Jos.
core
Advanced Healthcare Materials, EarlyView.This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang +13 more
wiley +1 more source
Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration
Advanced Healthcare Materials, EarlyView.Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu +4 more
wiley +1 more source
Kejahatan Narkoba sebagai Fenomena dari Transnational Organized Crime [PDF]
, 2013 Illicit drug trafficking undermine governance, institutions and societal cohesion. Drug traffickers typically seek the path where the rule of law is weak. In turn, drug-related crime deepens vulnerability to instability and poverty.
Jainah, Z. O. (Zainab)
core
Advanced Healthcare Materials, EarlyView.A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen +9 more
wiley +1 more source