Results 91 to 100 of about 2,023,961 (292)

Intracellular trafficking of new anticancer therapeutics: antibody–drug conjugates

open access: yes, 2017
Muhammad Kalim,1 Jie Chen,1 Shenghao Wang,1 Caiyao Lin,1 Saif Ullah,1 Keying Liang,1 Qian Ding,1 Shuqing Chen,2 Jinbiao Zhan1 1Department of Biochemistry and Genetics, School of Medicine, 2Department of Pharmaceutical Analysis, College of Pharmaceutical
Ullah S   +8 more
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An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

Human trafficking & temporary guestworker visas

open access: yes, 2023
This flier contains information about human trafficking and temporary guestworker ...
South Carolina Human Trafficking Task Force
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A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu   +14 more
wiley   +1 more source

2015 Annual report. 2016: Jan. 5.

open access: yes, 2016
Annual; Began with Jan. 2008.; "Report Prepared by the Permanent Commission on the Status of Women (PCSW)."; Volume for 2014 originally published in print and online with the title: Annual report, was reformatted online with the title: Recommendations to
Connecticut. Trafficking in Persons Council.
core   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Help eliminate human trafficking.; Other title: Trafico humano

open access: yes, 2013
Spanish version of: Help eliminate human trafficking.; "Mike DeWine, Ohio Attorney General."; "Created: 4/4/2013 ..."--Document properties screen.; "Protecting Ohio's Families.

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The Evaluation of Policy of Counteraction of Drug Trafficking from Afghanistan

open access: yesRUDN Journal of Political Science, 2013
The article is devoted to analysis of the main drug trafficking routes from Afghanistan, in particular “northern route”, which passes through states of the former Soviet Union.
- Hawa Mohammad Azam M
doaj  

Engineered Microvascular Model of the Blood–Brain–Tumor Barrier Reveals Endothelial Remodeling in Diffuse Midline Glioma

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett   +7 more
wiley   +1 more source

Drug trafficking penalties across the European Union: a survey of expert opinion. Technical report. [PDF]

open access: yes, 2017
The results of a study on national drug trafficking laws and their application in the Member States of the European Union are presented in this report.

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