Results 71 to 80 of about 2,023,961 (292)
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
A spatio-temporal analysis of forest loss related to cocaine trafficking in Central America
A growing body of evidence suggests that criminal activities associated with drug trafficking networks are a progressively important driver of forest loss in Central America. However, the scale at which drug trafficking represents a driver of forest loss
Steven E Sesnie +7 more
doaj +1 more source
KERJASAMA INDONESIA- MALAYSIA DALAM MENANGANI PEREDARAN NARKOBA DI PERBATASAN
Indonesia and Malaysia have close ties especially in their land borders, making it easier to access buying and selling that occurs between communities on the border. Especially in trade to drug trafficking that occurs in border areas such as the Entikong-
Ade Priangani +2 more
doaj +1 more source
Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni +19 more
wiley +1 more source
Hidden Resilience in the Life of Adolescents with Involvement in Drug Trafficking
This paper identifies hidden resilience processes among adolescents and young adults who have had involvement in drug trafficking. The participants were 551 adolescents and young people, aged 12-20 years (M = 16.01; SD = 1.548) from both genders, 55.4 ...
Alex Sandro Gomes Pessoa +3 more
doaj +1 more source
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Le marché des stupéfiants dans une société mondialisée / Drug trafficking in globalized society [PDF]
International co-operation treaties exist for decades, as well as the international drug traffic. However, they did not yet succeed in efficiently fighting international drug trafficking.
Brochu Serge, Perras Chantal
doaj
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch +5 more
wiley +1 more source
Drug Trafficking in the Americas [PDF]
The Bush Administration's Andean Drug Strategy in Historical Perspective, W. Walker III US-Andean Drug Policy, R. Perl The US Military and the War on Drugs, D. Mabry After San Antonio, B. Bagley The Size of the Illegal Drug Industry, F. Thoumi Drug Trafficking and Society in Colombia, A.
openaire +1 more source
Perceived Normalization of Drug Trafficking and Adolescent Substance Use on the US-Mexico Border. [PDF]
Valdez ES +5 more
europepmc +1 more source

