Results 51 to 60 of about 133,970 (253)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

War Zone Acapulco: Urban Drug Trafficking in the Americas

Contexto Internacional
Acapulco epitomises the (in)security of urban zones in the Americas whose geographical, political and economic divisions are exacerbated by the political economy and geopolitics of drug trafficking, as well as by militarised attempts to fight it. Various
Thiago Rodrigues, Mariana Kalil, Roberto Zepeda, Jonathan D Rosen   +3 more
doaj   +1 more source

Crack cocaine use and its relationship with violence and HIV

Clinics, 2009
OBJECTIVES: To evaluate crack cocaine use practices, risk behaviors associated with HIV infection among drug users, and their involvement with violence. INTRODUCTION: HIV infections are frequent among drug users due to risky sexual behavior.
Heraclito Barbosa de Carvalho, Sergio Dario Seibel   +1 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Hidden Resilience in the Life of Adolescents with Involvement in Drug Trafficking

Psicologia: Teoria e Pesquisa, 2019
This paper identifies hidden resilience processes among adolescents and young adults who have had involvement in drug trafficking. The participants were 551 adolescents and young people, aged 12-20 years (M = 16.01; SD = 1.548) from both genders, 55.4 ...
Alex Sandro Gomes Pessoa, Renata Maria Coimbra, Sílvia Helena Koller, Michael Ungar   +3 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A spatio-temporal analysis of forest loss related to cocaine trafficking in Central America

Environmental Research Letters, 2017
A growing body of evidence suggests that criminal activities associated with drug trafficking networks are a progressively important driver of forest loss in Central America. However, the scale at which drug trafficking represents a driver of forest loss
Steven E Sesnie, Beth Tellman, David Wrathall, Kendra McSweeney, Erik Nielsen, Karina Benessaiah, Ophelia Wang, Luis Rey   +7 more
doaj   +1 more source

KERJASAMA INDONESIA- MALAYSIA DALAM MENANGANI PEREDARAN NARKOBA DI PERBATASAN

Dinamika Global, 2020
Indonesia and Malaysia have close ties especially in their land borders, making it easier to access buying and selling that occurs between communities on the border. Especially in trade to drug trafficking that occurs in border areas such as the Entikong-
Ade Priangani, Kunkunrat Kunkunrat, Silvia Nurindah   +2 more
doaj   +1 more source

Legal perspectives on drug trafficking [PDF]

SSRN Electronic Journal, 2017
The two terms ‘trafficking’ and ‘personal consumption’ provide the conceptual framework for the international drug control regime. Neither term is defined. The principal disagreement behind the consensus reached on drug trafficking in the 1988 Convention was the extent to which conduct related to ‘personal consumption’ should fall within the scope of ...
openaire   +1 more source