Results 31 to 40 of about 133,970 (253)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Use of the Death Penalty for Drug Trafficking in the United States, Singapore, Malaysia, Indonesia and Thailand: A Comparative Legal Analysis

open access: yesLaws, 2013
This article assesses the use of capital punishment for drug trafficking and related crimes from a comparative perspective. Domestic narcotics legislation, as well as important drug trafficking cases in four Southeast Asian nations (Singapore, Malaysia ...
Yingyos Leechaianan, Dennis R. Longmire
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

‘You want to chill with the big boys’: Proverbs 21:4–7 and drug trafficking in Nigeria

open access: yesVerbum et Ecclesia, 2022
Although progress has been made in the study of Proverbs 21:4–7, existing literature is yet to shift focus on the relevance of the pericope in examining the different aspects of drug trafficking by Nigerians.
Favour C. Uroko, Success A. Nnadi
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Mexico: Remittances, Organized Crime and US Drug Overdose Crisis in Borderlands (2015-2021)

open access: yesNorteamérica, 2022
The present article aims at shedding some light to the question whether Mexico´s boom in remittances between 2015 and 2021 was the result of low rates of unemployment in the USA or of higher revenues of drug trafficking made by Mexican Criminal Groups ...
Gerardo Reyes Guzmán   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A Sociological Approach to Drug Use

open access: yesEIRP Proceedings, 2021
Lately, the illicit drug market in Romania has shown a continuous dynamics, registering an increase both in the availability of most types of drugs consumed and in the total amount of drugs confiscated, especially cocaine and cannabis. The availability
Angela-Mihaela Ene
doaj  

Theoretical and practical aspects of preventive work in the fight against drug addiction

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2020
The aim of the work is to study the theoretical and practical aspects of the emergence of drug addiction, types of preventive work in the fight against drug addiction, the peculiarities of its spread among adolescents. An assessment of the development of
Y. V. Platonova   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy