Results 201 to 210 of about 345,035 (349)

Linking Drug Trafficking to Insecurity and Conflict Dimensions in West Africa: A Comparative Analysis of Guinea- Bissau, Guinea Conakry and Nigeria

, 2019
Emmanuel Uzuegbu-Wilson
openalex   +1 more source

Both brefeldin A and latrunculin B treatment induces cytoplasmic aggregation of plasma membrane-associated proteins in epidermal cells, but not in columella cells. [PDF]

Plant Signal Behav
Chen A, Wang Q, Sheng X.
europepmc   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

Advanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin, Dingqin Cai, Chunli Jian, Yaxian Qi, Linpeng Zheng, Qiao Yang, Longyao Zhang, Diangang Chen, Lingchen Li, Ping Cai, Lingyou Sun, Luping Zhang, Jianguo Sun   +12 more
wiley   +1 more source

Drug Trafficking in Relation to Global Shipping Network

, 2023
Louise Leibbrandt, Shilun Zhang, Marijn Roelvink, Stan Bergkamp, Xinqi Li, Lieselot Bisschop, Karin van Wingerde, Huijuan Wang   +7 more
openalex   +2 more sources

Disruption of Synaptic Vesicle Trafficking in Alzheimer's and Parkinson's Disease: Mechanisms and Therapeutic Implication. [PDF]

Int J Mol Sci
Zhu Y, Zhao L, Li Y, Tian M, Liao Y, Huang J, Guo P, Xie Y.   +7 more
europepmc   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Regional Mechanisms Against Illegal Drug Trafficking

, 2020
Shukurov Izzatullo Hikmatullo Ogli
openalex   +2 more sources

Drug trafficking in Russia and in the world during the pandemic COVID-19

, 2022
Margarita E. Pozdniakova, V. V. Bryuno
openalex   +1 more source

Subcellular nanoparticle trafficking investigated with label-free, live cell imaging. [PDF]

Nanoscale Horiz
Nelson EB, Covarrubias G, Nabar N, Gomerdinger VF, Scott A, Hammond PT, Straehla JP.   +6 more
europepmc   +1 more source

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

Advanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun, Qihong Li, Bixi Wang, Gang Wang, Ying Xue, Yibing Liang, Chenhe Hu, Zhenyu Wang, Xiaoge Gao, Haiheng Xu, Jun Song, Hailong Li, Liantao Li, Xiaoxiao Liu, Patrick Ming‐Kuen Tang, Qing Zhang   +15 more
wiley   +1 more source