Hungry for Knowledge: Octopamine Signaling Regulates Hunger‐Enhanced Olfactory Learning
Researchers demonstrate that hunger state facilitates both aversive and appetitive olfactory learning. Two distinct octopamine signaling pathways are involved in aversive or appetitive memory formation in the hunger state. And, hunger state also facilitates the formation of both types of memories via an evolutionarily conserved norepinephrine (the ...
Huijuan Zhao +14 more
wiley +1 more source
Abdominal Pain and Vaginal Discharge: An Eye-Opening Simulation Case about Human Trafficking. [PDF]
Exeni McAmis NE +3 more
europepmc +1 more source
Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Structure and dynamics mapping of illicit firearms trafficking using artificial intelligence models. [PDF]
Valdivia-Granda WA.
europepmc +1 more source
Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu +8 more
wiley +1 more source
Alleviation of ER stress via targeted genetic engineering enhances recombinant ovalbumin secretion in <i>Saccharomyces cerevisiae</i>. [PDF]
Yoon EB +5 more
europepmc +1 more source
Human Trafficking in the Drug Trade: Lessons for Attorneys from the Mary Jane Veloso Case
Felicity Gerry
openalex
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin +19 more
wiley +1 more source
<i>ITGA4</i> genetic variants as a predictor of therapeutic responsivity to autoimmune diseases. [PDF]
De Matos MD +5 more
europepmc +1 more source

