Results 281 to 290 of about 4,232,654 (389)

The process of desecuritization of drug trafficking in Unasur

, 2014
Mariana Preta Oliveira de Lyra
openalex   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

Advanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

The threat from Transnational Crime in Southeast Asia: Drug Trafficking, Human Smuggling and Trafficking and sea piracy.

Revista UNISCI, 2003
Ralf Emmers
doaj  

Ionic Mechanisms of Two-Pore Channel Regulation of Vesicle Trafficking. [PDF]

Cells
Zhang H, Zhu MX.
europepmc   +1 more source

Forensic characteristics of the prevalence, subject and method of illegal drug trafficking committed using the Internet

A. E. Grigorieva, A. A. Antipina
openalex   +2 more sources

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

Recent advancement in polymeric nanoparticles for oral chemotherapy: Transforming cancer treatment. [PDF]

Bioimpacts
Mangu K, Gudeli R, Rizwanullah M.
europepmc   +1 more source

Rod‐Shaped Nanotherapeutics Alleviate Rheumatoid Arthritis by Precisely Disrupting Platelet‐Mediated Pathological Crosstalk via a Morphology‐Dependent Manner

Advanced Science, EarlyView.
Owing to the margination effect, rod‐shaped nanoparticles exhibit markedly enhanced co‐localization with endothelial‐adherent platelets (PLTs) under dynamic blood flow. When internalized by PLTs, rod‐shaped PNR@Res inhibit FAK and PI3K/AKT signaling in a morphology‐dependent manner, thereby disrupting their pathological crosstalk with various ...
Bin Zhang, Yuanyi Hua, Xin Wen, Zhumei Liao, Jianheng Ren, Yajun Weng, Qin Wang   +6 more
wiley   +1 more source

The Glymphatic-Immune Axis in Glioblastoma: Mechanistic Insights and Translational Opportunities. [PDF]

Int J Mol Sci
Fiallo Arroyo J, Leon-Rojas JE.
europepmc   +1 more source