Results 211 to 220 of about 339,354 (311)

Drug Utilization Review Board Annual Report 2007-2008

, 2008
New Jersey. Drug Utilization Annual Review Board
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Value of Pharmacogenetic Testing Assessed with Real-World Drug Utilization and Genotype Data. [PDF]

Clin Pharmacol Ther
Litonius K, Kulla N, Falkenbach P, Kristiansson K, Tarkiainen EK, Ukkola-Vuoti L, Cajanus K, Korhonen M, Khan S, Sistonen J, Orpana A, Lindstedt M, Nyrönen T, Perola M, Turpeinen M, Kytö V, Tornio A, Niemi M.   +17 more
europepmc   +1 more source

Drug Utilization Review Board Annual Report 2008-2009

, 2009
New Jersey. Drug Utilization Annual Review Board
core  

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Antidepressant drug switching in the Swiss population with a focus on Escitalopram and drugs with pharmacogenetic dosing guidelines: a drug utilization study using claims data. [PDF]

Pharmacogenomics J
Roth MM, Meier CR, Huber CA, Meyer Zu Schwabedissen HE, Allemann S, Schneider C.   +5 more
europepmc   +1 more source

Drug Utilization Review Board Annual Report 2009-2010

, 2010
New Jersey. Drug Utilization Annual Review Board
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Trends of lipid-lowering drug utilization, treatment intensity and LDL-C target attainment in adults with diabetes and non-dialysis chronic kidney disease in Hong Kong. [PDF]

Lancet Reg Health West Pac
Huang Y, Yang A, Shi M, Yu J, Wu H, Lui JNM, Kong APS, Ma RCW, Luk AOY, Ke C, Chan JCN, Chow E.   +11 more
europepmc   +1 more source

Drug Utilization Review Board Annual Report 2011-2012

, 2012
New Jersey. Drug Utilization Annual Review Board
core