Results 221 to 230 of about 703,096 (358)
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Drug Utilization and Potentially Inappropriate Prescriptions Assessment Among Discharged Pediatric Patients in a Tertiary Care Hospital. [PDF]
Maratha Muthu M +4 more
europepmc +1 more source
Molecular cancer prevention: Intercepting disease
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Off‑label and unapproved pediatric drug utilization: A meta‑analysis. [PDF]
Yuan X, Gao J, Yang L, Tan Y, Bajinka O.
europepmc +1 more source
We have the Tools to End HIV: Benefits, Barriers, and Solutions to Expanded Utilization of Pre-exposure Prophylaxis (PrEP) in the US Deep South [PDF]
Ervin, Jason +2 more
core +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Intranasal corticosteroid users in The Netherlands: A drug utilization study. [PDF]
Rollema C +4 more
europepmc +1 more source

