Results 241 to 250 of about 703,096 (358)

Studies of Drug Utilization

, 2012
David Lee, Ulf Bergman
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Prescription Drug Utilization and Spending by Race, Ethnicity, Payer, Health Condition, and US State.

JAMA Health Forum
Sahu M, Wagner TD, Thomson A, Beauchamp M, Campbell JD, Crosby S, DeJarnatt D, Lescinsky H, Salih RK, Taylor K, Weil M, Dwyer-Lindgren L, Haakenstad A, Scott JW, Stergachis A, Essien UR, Dieleman JL.   +16 more
europepmc   +1 more source

Trends of lipid-lowering drug utilization, treatment intensity and LDL-C target attainment in adults with diabetes and non-dialysis chronic kidney disease in Hong Kong. [PDF]

Lancet Reg Health West Pac
Huang Y, Yang A, Shi M, Yu J, Wu H, Lui JNM, Kong APS, Ma RCW, Luk AOY, Ke C, Chan JCN, Chow E.   +11 more
europepmc   +1 more source

Drug Delivery by Utilizing Oligopeptide Transporter.

, 1999
Ikumi Tamai
openalex   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Acetaminophen in Pregnancy: A Population-Level Drug-Utilization Study of Prescription-Based Acetaminophen Use Among Pregnant Women in Denmark From 2001 to 2023. [PDF]

Basic Clin Pharmacol Toxicol
Pflugfelder S, Gram EB, Damkier P.
europepmc   +1 more source

Gaps in the Implementation of Drug Utilization Programs in Pakistan: A Systematic Review [PDF]

Syed Muhammad Ali, Wafa Ishaq, Ramla Shabbir, Rukhsar Imran   +3 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Drug utilization pattern and cost analysis of antidiabetic drugs among type 2 diabetic patients at a teaching hospital in South India: A prospective observational study. [PDF]

J Family Med Prim Care
Kavitha S, Nishanthi A, Navabalan V, Manickam S, Dhamodharan A, Subramanian G.   +5 more
europepmc   +1 more source