Results 251 to 260 of about 703,096 (358)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Drug Utilization of Rifaximin-α in Patients with Hepatic Encephalopathy: Evidence from Real Clinical Practice in Italy. [PDF]

Medicina (Kaunas)
Perrone V, Usala M, Veronesi C, Cappuccilli M, Degli Esposti L.   +4 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Multiple sclerosis patient-reported outcomes of pharmacotherapy clinic drug utilization programs; a controlled pre-post study of self-injectable disease-modifying therapies. [PDF]

BMC Res Notes
Mohammadnezhad G, Khajeamiri Y, Khosravani S, Pourbala H, Esmaily H.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Impact of supply chain disruptions and drug shortages on drug utilization: A scoping review protocol. [PDF]

PLoS One
Santhireswaran A, Ho M, Fuller K, Gaudette E, Burry L, Tadrous M.   +5 more
europepmc   +1 more source

Drug Utilization Analysis of Analgesics and Adjuvants Used in Pain Management [PDF]

Sarad Pawar Naik Bukke, Thalluri Gopalakrishnaiah, Hope Onohuean, Pathange Bharghava Bhushan Rao, Nandini Nandimandalam, Malakapogu Ravindra Babu, Kusuma Praveen Kumar   +6 more
openalex   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Scoping review of anticancer drug utilization in lung cancer patients at the end of life. [PDF]

Clin Transl Oncol
Szigethy E, Merzah M, Sola I, Urrútia G, Bonfill X.   +4 more
europepmc   +1 more source

Purchasing and inventory control system of drugs utilized ABC analysis theory using personal computer.

, 1986
Keizo ISHIMOTO, K. Hironaga, Akira Koshiro, SADANORI NAKAMURA   +3 more
openalex   +2 more sources