Results 41 to 50 of about 84,078 (314)

Danshen: A Popular Chinese Cardiac Herbal Drug

Journal of the American College of Cardiology, 2006
The recently published document in JACC on complementary and integrative medicine ([1][1]) left out one very important herbal drug, danshen. Because it is believed to have properties of improving microcirculation, increasing coronary blood flow, suppressing thromboxane formation, inhibiting ...
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EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
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Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies

Chinese Medicine, 2021
The Coronavirus disease 2019 (COVID-19) pandemic is still spread and has made a severe public health threat around the world. To improve disease progression, emerging Chinese herbal compounds were used in clinical practice and some agents have proven ...
Mu-Feng Xiang, Cheng-Tao Jin, Li-Hua Sun, Zhi-Hui Zhang, Jing-Jing Yao, Liu-Cheng Li   +5 more
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Cytochrome P450 enzyme mediated herbal drug interactions (Part 2) [PDF]

, 2014
To date, a number of significant herbal drug interactions have their origins in the alteration of cytochrome P450 (CYP) activity by various phytochemicals. Among the most noteworthy are those involving St.
Phopin, Kamonrat, Prachayasittikul, Virapong, Wanwimolruk, Sompon   +2 more
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Effects of Chinese Herbal Medicines on Intestinal Drug Absorption

YAKUGAKU ZASSHI, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +3 more sources

Rupestonic Acid of Artemisia Rupestris L. Extract Treats Pulmonary Fibrosis in COPD by Targeting TGF‐β1

Advanced Science, EarlyView.
RA of EEAR inhibits TGF‐β1 ubiquitination and changes conformation by target binding TGF‐β1, regulating TGF‐β1/Smad2/3 signaling pathway. Thus it down‐regulated downstream protein expression, inhibited EMT and collagen deposition of ECM, in order to EEAR preventing PF in COPD.
Lingfeng Peng, Lulu Zhang, Yimeng Fan, Sijuan Huang, Qingyu Zhao, Chao Han, Zhihui Hao   +6 more
wiley   +1 more source

Effects of alkaloids on peripheral neuropathic pain: a review

Chinese Medicine, 2020
Neuropathic pain is a debilitating pathological pain condition with a great therapeutic challenge in clinical practice. Currently used analgesics produce deleterious side effects.
Chunhao Zhu, Ning Liu, Miaomiao Tian, Lin Ma, Jiamei Yang, Xiaobing Lan, Hanxiang Ma, Jianguo Niu, Jianqiang Yu   +8 more
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Artemisinin: From Chinese Herbal Medicine to Modern Chemotherapy [PDF]

, 2019
Malaria is a disease that has blighted humankind since early times. The first antimalarial treatment available to Europeans was the dried bark of the cinchona tree from Peru. The main problem in its use was adulteration by other material.
Butler, Anthony
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Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

Advanced Science, EarlyView.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan, Huzi Zhao, Pei Zhang, Pengfei Yu, Yunfei Ji, Gang Chen, Hongli Jin, Yanfang Liu, Jin Liu, Zhe‐Sheng Chen, Aiping Lyu, Xinmiao Liang, Yang Chen   +12 more
wiley   +1 more source

Traditional Chinese medicine-associated nephrotoxicity and the importance of herbal interactions – An overview

Pharmacological Research - Modern Chinese Medicine, 2022
Herbal traditional Chinese medicines (TCMs) are an increasingly popular alternative therapy globally. Due to the complex chemical composition of herbal products, and with research showing that consumers from Western countries are more likely to take ...
Susan M. Britza, Roger W. Byard, Ian F. Musgrave   +2 more
doaj   +1 more source