Results 51 to 60 of about 84,600 (310)

Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies

Chinese Medicine, 2021
The Coronavirus disease 2019 (COVID-19) pandemic is still spread and has made a severe public health threat around the world. To improve disease progression, emerging Chinese herbal compounds were used in clinical practice and some agents have proven ...
Mu-Feng Xiang, Cheng-Tao Jin, Li-Hua Sun, Zhi-Hui Zhang, Jing-Jing Yao, Liu-Cheng Li   +5 more
doaj   +1 more source

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source

Polygonatum cyrtonema Hua fructan ameliorates ulcerative colitis via gut microbiota modulation and follistatin targeting

npj Science of Food
Ulcerative colitis (UC) is a chronic inflammatory bowel disease with persistent colonic inflammation and inadequate therapeutic options. The medicinal and edible plant Polygonatum cyrtonema Hua from Jiuhua Mountain contains polysaccharides with potent ...
Qiangbao Xu, Qiuyue Lv, Zhu Yang, Yiping Yang, Zihan Li, Yingying Zhang, Lingzhi Chen, Sumiao Zhan, Hui Che, Guodong Wang, Jiangping Wu, Jun Han   +11 more
doaj   +1 more source

Traditional Chinese medicine-associated nephrotoxicity and the importance of herbal interactions – An overview

Pharmacological Research - Modern Chinese Medicine, 2022
Herbal traditional Chinese medicines (TCMs) are an increasingly popular alternative therapy globally. Due to the complex chemical composition of herbal products, and with research showing that consumers from Western countries are more likely to take ...
Susan M. Britza, Roger W. Byard, Ian F. Musgrave   +2 more
doaj   +1 more source

Cytochrome P450 enzyme mediated herbal drug interactions (Part 2) [PDF]

, 2014
To date, a number of significant herbal drug interactions have their origins in the alteration of cytochrome P450 (CYP) activity by various phytochemicals. Among the most noteworthy are those involving St.
Phopin, Kamonrat, Prachayasittikul, Virapong, Wanwimolruk, Sompon   +2 more
core  

Concurrent use of prescription drugs and herbal medicinal products in older adults: A systematic review [PDF]

, 2017
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction ...
A Cherubini, A Djuv, A Fugh-Berman, A Gonzalez-Stuart, A Robinson, A Tsang, AA Izzo, AA Izzo, AA Mangoni, AM Loya, Barbara Wider, C Batanero-Hernán, CA Parkman, CC Peng, Claire Goodman, Commission of the European Communities, DH Mehta, DM Qato, DM Qato, DW Kaufman, E Vacas Rodilla, EC Davies, EM Williamson, FP Turkmenoglu, G Nyborg, GW Elmer, J Jerez-Roig, J Kavanagh, J Kennedy, J Ly, J Peklar, J Sultana, JE Souza Silva de, JJ Bruno, JM Dergal, JS Marinac, K Radimer, KA Vickers, L Howell, L Shamseer, L Shane-McWhorter, Leala K. Watson, MA Raji, ME Levine, MHRA, Ipsos MORI, MS Lantz, N Lynch, N Samuels, P Gardiner, P Posadzki, PH Canter, R Delgoda, RL Nahin, S Hilmer, S Singh, S Yoon, SJ Blalock, SJ Yoon, SL Yoon, SR Singh, T Agbabiaka, Taofikat B. Agbabiaka, The Joanna Briggs Institute, W Leiss, X-L Zhang, Z Munn   +65 more
core   +2 more sources

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

Advanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova, Michael Nicholls, Nicola Russo, Gueorgui Mihaylov, Konstantin Nikolic   +4 more
wiley   +1 more source

Drug innovation via integration of traditional Chinese and Western medicine

Science of Traditional Chinese Medicine
. Innovative drugs are defined as new chemical entities that play a vital role in the treatment and maintenance of human health. While single-target innovative drugs have achieved notable success, they face limitations in addressing the increasingly ...
Zhineng Li, Le Yang, Ling Kong, Hui Sun, Ye Sun, Xiangmei Chen, Fengting Yin, Guangli Yan, Xijun Wang   +8 more
doaj   +1 more source

Review of the Efficacy and Mechanisms of Traditional Chinese Medicines as a Therapeutic Option for Ionizing Radiation Induced Damage

Frontiers in Pharmacology, 2021
Ionizing radiation damage refers to acute, delayed, or chronic tissue damage associated with ionizing radiation. Specific or effective therapeutic options for systemic injuries induced by ionizing radiation have not been developed.
Xiaomeng Zhang, Xiaoying Chen, Lei Wang, Changhao He, Zhongyu Shi, Qian Fu, Wenhui Xu, Shujing Zhang, Sumin Hu   +8 more
doaj   +1 more source

Current status of herbal and their future perspectives [PDF]

, 2007
Traditional medicine is the synthesis of therapeutic experience of generations of practicing physicians of indigenous systems of medicine. Throughout the history of mankind, many infectious diseases have been treated with herbals.
Ponnampalam Gopalakrishnakone, Ramar Perumal R. Samy   +1 more
core   +1 more source