Results 71 to 80 of about 181,905 (281)

Glucose‐Responsive and Analgesic Gel for Diabetic Subcutaneous Abscess Treatment by Simultaneously Boosting Photodynamic Therapy and Relieving Hypoxia

Advanced Science, EarlyView.
The work constructs a glucose‐triggered gel for diabetic abscess treatment. The results demonstrate that the gel catalyzes glucose into oxygen, alleviates the hypoxia, and ensures sufficient ROS generation to combat pathogenic bacteria. Simultaneously, borneol within the gel can enhance the antibacterial activity of ROS and alleviate pain in patients ...
Bin Huang, Honglin An, Jianfeng Chu, Shiqi Ke, Jing Ke, Yiman Qiu, Jieping Zhang, Hanqi Zhu, Jiahui Lin, Minguang Yang, Dongliang Yang, Xuejiao Song, Weilin Liu   +12 more
wiley   +1 more source

In Situ Assembly of Fluorogenic RNA for Screening Natural Anti‐Liver Fibrosis Products via Dynamic Visualization of COL1A1 mRNA

Advanced Science, EarlyView.
This study introduces an in situ assembly of fluorogenic RNA approach for screening natural anti‐liver fibrosis compounds and dynamic visualization of endogenous COL1A1 mRNA in live cells. It offers a simple, cost‐effective approach of visualizing RNA dynamics and conducting drug screening in live cells, presenting a significant potential for the ...
Rui Bai, Li‐Zeng Zhu, Changfa Shao, Zheng Yin, Qun Liu, Yu Gu, Bin Liu   +6 more
wiley   +1 more source

Assessment of suitable region of Asparagus cochinchinensis (Lour.) Merr. under different climatic conditions in China by the MaxEnt model and HPLC analysis

Ecology and Evolution
Asparagus cochinchinensis is a member of the Asparagaceae family whose medicinal part is the dried root tuber. The distribution of A. cochinchinensis and its secondary metabolites are closely associated with environmental factors, such as climate and ...
Tong Zhang, Xiangyang Lv, Qian Zhao, Caijuan Zhang, Honglin Yin, Shuyu Deng, Gui Yan, Guangzhi Wang, Xiaoyan Cao, Hong Ou, Gang Shen   +10 more
doaj   +1 more source

A comparison of the efficacy of Chinese herbal medicines in the treatment of primary dysmenorrhea

Medicine, 2019
Introduction: Chinese herbal medicines (CHM) have been commonly used in the treatment of primary dysmenorrhea in East Asia. Several systematic reviews have been conducted to assess the clinical efficacy of CHM in the treatment of primary dysmenorrhea ...
Li-Xing Gao, Zhuoran Xiao, Chunhua Jia, Wei Wang   +3 more
semanticscholar   +1 more source

Helicobacter pylori Detection Based on Synergistic Electromagnetic and Chemical Enhancement of Surface‐Enhanced Raman Scattering in 3D Hotspot‐Activated Gold Nanorods/Nano Mica Platelets/ZnO Quantum Dots

Advanced Science, EarlyView.
Gold nanorods hybridized with nano mica platelets and ZnO quantum dots are used for the rapid, sensitive, selective, and reproducible surface‐enhanced Raman scattering‐based detection of Helicobacter pylori in different scenarios. The origin of this high performance is ascribed to the synergy between the three operational enhancement mechanisms and the
Ming‐Chang Lu, Yung‐Chi Yang, Chia‐Jung Lee, Chih‐Wei Chiu   +3 more
wiley   +1 more source

Bimetallic Plasmonic Nanozyme‐Based Microneedle for Synergistic Ferroptosis Therapy of Melanoma

Advanced Science, EarlyView.
A microneedle (MN) patch that integrates novel bimetallic plasmonic nanozyme (BPNzyme) and traditional Chinese medicine β‐elemene (β‐ELE) has been rationally designed for ferroptosis pathway‐dependent combined therapy of melanoma. Abstract Melanoma is the most common malignant skin tumor, characterized by complexity, invasiveness, and heterogeneity ...
Wei Duan, Keying Xu, Yue Gao, Sheng Huang, Xueqian Xia, Xiang Liu, Shuangxue Pan, Chunpeng Jiao, Weijian Cheng, Yong Guo, Jingwen Zhao, Jia‐Wei Shen   +11 more
wiley   +1 more source

Cordycepin Prevents Hyperlipidemia in Hamsters Fed a High-Fat Diet via Activation of AMP-Activated Protein Kinase

Journal of Pharmacological Sciences, 2010
Hyperlipidemia is a major risk factor for cardiovascular diseases. In this study, we investigated the potential effects of cordycepin (3′-deoxyadenosine), a bioactive component of the fungus Cordyceps militaris, on hyperlipidemia.
Peng Guo, Qu Kai, Jian Gao, Ze-qin Lian, Chong-ming Wu, Cheng-ai Wu, Hai-bo Zhu   +6 more
doaj  

Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas

Advanced Intelligent Systems, EarlyView.
A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang, Dingsi Xiang, Shengli Mi, Jiajun Huang   +3 more
wiley   +1 more source

Non-coding RNAs: targets for Chinese herbal medicine in treating myocardial fibrosis

Frontiers in Pharmacology
Cardiovascular diseases have become the leading cause of death in urban and rural areas. Myocardial fibrosis is a common pathological manifestation at the adaptive and repair stage of cardiovascular diseases, easily predisposing to cardiac death.
Minghui Wang, Minghui Wang, Maocai Yan, Liqiang Tan, Xiaona Zhao, Xiaona Zhao, Guoqing Liu, Guoqing Liu, Zejin Zhang, Zejin Zhang, Jing Zhang, Honggang Gao, Wei Qin   +12 more
doaj   +1 more source

Why is Research on Herbal Medicinal Products Important and How Can We Improve Its Quality?

Journal of Traditional and Complementary Medicine, 2014
Research on herbal medicinal products is increasingly published in “Western” scientific journals dedicated primarily to conventional medicines. Publications are concerned mainly not only on the issues of safety and interactions, but also on efficacy.
Olavi Pelkonen, Qihe Xu, Tai-Ping Fan
doaj   +1 more source