Results 21 to 30 of about 9,616,743 (356)

Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: Functional and therapeutic implications [PDF]

open access: yes, 2013
This article is made available through the Brunel Open Access Publishing Fund. © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.CLU (clusterin) is a tumor suppressor gene that we have previously shown to be negatively modulated ...
Cantilena, S   +8 more
core   +1 more source

RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges

open access: yesPharmacological Reviews, 2020
RNA-based therapies, including RNA molecules as drugs and RNA-targeted small molecules, offer unique opportunities to expand the range of therapeutic targets.
A. Yu, Y. Choi, Mei-Juan Tu
semanticscholar   +1 more source

Survey and analysis of the availability and affordability of essential drugs in Hefei based on WHO / HAI standard survey methods

open access: yesBMC Public Health, 2020
Background The 2018 edition of the National Essential drugs List came into effect in September 2018. Relevant policies require that all primary medical and health institutions should supply national essential drugs, while secondary and tertiary medical ...
Zuojun Dong, Qiucheng Tao, Guojun Sun
doaj   +1 more source

Divergent strategy for the synthesis of α-aryl-substituted fosmidomycin analogues [PDF]

open access: yes, 2007
Fosmidomycin is the first representative of a new class of antimalarial drugs acting through inhibition of 1-deoxy-D-xylulose 5-phosphate ( DOXP) reductoisomerase (DXR), an essential enzyme in the non-mevalonate pathway for the synthesis of isoprenoids ...
Devreux, Vincent   +5 more
core   +2 more sources

Challenges in maintaining treatment services for people who use drugs during the COVID-19 pandemic

open access: yesHarm Reduction Journal, 2020
The impact of COVID-19 across health services, including treatment services for people who use drugs, is emerging but likely to have a high impact. Treatment services for people who use drugs provide essential treatment services including opiate agonist ...
A. Dunlop   +11 more
semanticscholar   +1 more source

RESEARCH-BASED DEVELOPMENT OF CONSUMER DRUG INFORMATION PAMPHLET AT TRIBHUVAN UNIVERSITY TEACHING HOSPITAL IN NEPAL

open access: yesJournal of Nepal Medical Association, 2003
Considering the generally low priority given to educating consumers in Nepal and also as a part of its commitment towards consumer awareness, the Drug Information Unit of Tribhuvan University Teaching Hospital (TUTH) developed and distributed a consumer ...
Mohan P Joshi   +4 more
doaj   +1 more source

Pharmacological and clinical application of heparin progress: An essential drug for modern medicine.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021
Heparin is the earliest and most widely used anticoagulant and antithrombotic drug that is still used in a variety of clinical indications. Since it was discovered in 1916, after more than a century of repeated exploration, heparin has not been replaced ...
Min Qiu   +9 more
semanticscholar   +1 more source

Essential medicine list in India, 2022: A recent update [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2023
The National List of Essential Medicines (NLEM) serves as the primary guide for determining whether a drug is essential and setting price limits to keep drugs within reach of everyone.The list of necessary medications must be country-specific, that is ...
U. Sharath   +2 more
doaj  

Assessment of e-aushadhi program (drug inventory e-health initiative in Rajasthan) using benefit evaluation framework

open access: yesJournal of Family Medicine and Primary Care, 2022
Background: E-aushadhi is a drug supply chain management initiative of the Rajasthan government. This study is conducted to assess this e-health program as evidence is lacking in this context. Methods: A mix-method study was conducted.
Neha Mantri   +6 more
doaj   +1 more source

Role of the Calcium Plateau in the Neuronal Injury and Behavioral Morbidities Following Organophosphate Intoxication [PDF]

open access: yes, 2016
Organophosphate (OP) chemicals include nerve agents and pesticides, and there is a growing concern of OP based chemical attacks against civilians. Current antidotes are essential in limiting immediate mortality associated with OP exposure.
Battaglia F.P.   +8 more
core   +2 more sources

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