Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Alveolar soft part sarcoma (ASPS) is a rare soft tissue sarcoma occurring most commonly in adolescence and young adulthood. Methods We present the clinical characteristics, treatments, and outcomes of patients with newly diagnosed ASPS enrolled on the Children's Oncology Group study ARST0332.
Jacquelyn N. Crane +11 more
wiley +1 more source
The synthesis of potential antimalarials. Derivatives of pantoyltaurine [PDF]
, 1946 The general hypothesis as to the mode of action of chemotherapeutic agents, which has been formulated by Fildes, Woods, McIlwain, and others (2), offers a rational and useful guide to the design of new drugs. Thus, bacteriostasis is pictured as caused by
Koepfli, J. B. +4 more
core
Avaliação da assistência farmacêutica na atenção primária no Distrito Federal [PDF]
, 2005 OBJETIVO: O acesso a medicamentos e seus serviços é indispensável às ações de saúde e um direito do cidadão segundo a política de medicamentos e a legislação brasileira.
Naves, Janeth de Oliveira Silva +1 more
core +2 more sources
Screening of Synergic Interactions of Anti-Angiogenic and Anti-Tumor Compounds [PDF]
, 2015 Solid cancers have several common characteristics that Hanahan & Weinberg named as the hallmarks of cancer. Angiogenesis is an essential hallmark of cancer because tumor cells need oxygen and nutrients delivered by the vascular system.
García-Vilas García, Javier Alejandro +2 more
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Can NGOs Regulate Medicines Markets? Social Enterprise in Wholesaling, and Access to Essential Medicines. [PDF]
, 2011 Citizens of high income countries rely on highly regulated medicines markets. However low income countries' impoverished populations generally struggle for access to essential medicines through out-of-pocket purchase on poorly regulated markets; results ...
Chaudhuri, Sudip +2 more
core +4 more sources
Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano +7 more
wiley +1 more source
Adenovirus-Mediated Sensitization to the Cytotoxic Drugs Docetaxel and Mitoxantrone Is Dependent on Regulatory Domains in the E1ACR1 Gene-Region [PDF]
, 2012 Oncolytic adenoviruses have shown promising efficacy in clinical trials targeting prostate cancers that frequently develop resistance to all current therapies.
Daniel Öberg +7 more
core +10 more sources
Zaporožskij Medicinskij Žurnal, 2012 Comparative analysis of WHO Model List of Essential Medicines, “Liste des spécialités pharmaceutiques remboursables aux assurés sociaux” and Ukrainian National Formulary concerning the medicines prescribed in cases of pregnancy complications was ...
M. L. Syatynya, E. O. Kovalenko
doaj +1 more source
Still Taxed to Death: An Analysis of Taxes and Tariffs on Medicines, Vaccines and Medical Devices [PDF]
This paper examines the role that tariffs, domestic taxes, and regulatory requirements pose on access to essential drugs, vaccines and devices for the diseases that afflict the developing world.
Bate, Roger +2 more
core +1 more source
Immunogenic Modulations Induced by Prospective Anti-Malarial Herbal Extracts in Murine Model [PDF]
, 2010 Keeping in view the ever increasing problem of drug resistance and affordability of the antimalarial drugs by the poor mass, herbal medicines can become an important and alternative sustainable strategy for malaria treatment.
Chinmoy Karjee +11 more
core +1 more source