Results 241 to 250 of about 104,914 (293)
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Investigational Antiretroviral Drugs
Recent Patents on Anti-Infective Drug Discovery, 2008HIV disease is a chronic infection that requires lifelong treatment with the aim of suppressing the circulating viral load in order to improve the host immune status. The development of safe and effective antiretroviral agents with unique resistance profiles or novel mechanisms of action are an important goal for the long-term management of HIV ...
Sourav, Sen +4 more
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Drug Investigation Regulations
JAMA: The Journal of the American Medical Association, 1968ABSTRACT To the Editor:— Dr. Brown's interpretation of our regulations (203: 857, 1962) states that the investigator must "retain all records until two years after his study ends or after the New Drug Application (NDA) is approved." The regulation reads "... or if the application is not approved, until two years after the investigation is discontinued."
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American Journal of Health-System Pharmacy, 1968
Clifton J. Lotiolois, Roger Anderson
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Clifton J. Lotiolois, Roger Anderson
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Investigating beneficial drug reactions
BMJ, 2012Abstract OBJECTIVES The aim of this study was to explore the full range of tricuspid valve regurgitation velocity (TRV) at rest and with exercise in disease free individuals. Additionally we examined the relationship of stroke volume (SV), cardiac output (CO) and TRV to exercise capacity. BACKGROUND Doppler evaluation of TRV can be used to estimate
Jim, Parle, Nick, Ross, June, Jones
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Investigational drug labeling variability
Clinical Trials, 2019Background/aims In comparison with commercial drugs, there are few regulations concerning the labeling of investigational drugs. This leads to variability in their content and layout. This increases the risk of errors during storage, validation, compounding, dispensing and administration.
Amélie Duhamel +4 more
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Investigational drugs for hyperuricemia
Expert Opinion on Investigational Drugs, 2015The unmet need and the growing prevalence of hyperuricemia and its complications worldwide have pushed investigators to identify new agents to manage hyperuricemia.This review discusses the drugs in preclinical and early clinical trials for hyperuricemia, their mechanisms of action and available results. This article reviews a total of 10 novel agents:
Hania, Shahid, Jasvinder A, Singh
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Sarcoidosis: Drugs under Investigation
Seminars in Respiratory and Critical Care Medicine, 2017AbstractEtiology of sarcoidosis is still elusive, yet there has been considerable progress in various areas of basic and clinical research. In this review, we focus on ongoing or recently completed clinical–pharmacological studies in patients with sarcoidosis.
Schupp, Jonas Christian +3 more
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