Results 301 to 310 of about 9,783,797 (388)

Current landscape of innovative drug development and regulatory support in China. [PDF]

open access: yesSignal Transduct Target Ther
Tan R   +7 more
europepmc   +1 more source

mRNA-based therapeutics — developing a new class of drugs

open access: yesNature reviews. Drug discovery, 2014
U. Şahin, K. Karikó, Ö. Türeci
semanticscholar   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

open access: yesFEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis   +3 more
wiley   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Quantifying the chemical beauty of drugs.

open access: yesNature Chemistry, 2012
G. R. Bickerton   +4 more
semanticscholar   +1 more source

Report on Drugs [PDF]

open access: yesJournal of AOAC INTERNATIONAL, 1925
openaire   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

open access: yesFEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li   +5 more
wiley   +1 more source

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