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Dry powder inhaler formulation.
Respiratory care, 2005A drug product combines pharmacologic activity with pharmaceutical properties. Desirable performance characteristics are physical and chemical stability, ease of processing, accurate and reproducible delivery to the target organ, and availability at the site of action.
Martin J, Telko, Anthony J, Hickey
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Alternative carriers in dry powder inhaler formulations
Drug Discovery Today, 2014The aerosolization efficiency of a powder is highly dependent on carrier characteristics, such as particle size distribution, shape and surface properties. The main objective in the inhalation field is to achieve a high and reproducible pulmonary deposition.
Yahya, Rahimpour +2 more
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Dry powder inhalers for pulmonary drug delivery
Expert Opinion on Drug Delivery, 2004The pulmonary route is an interesting route for drug administration, both for effective local therapy (asthma, chronic obstructive pulmonary disease or cystic fibrosis) and for the systemic administration of drugs (e.g., peptides and proteins). Well-designed dry powder inhalers are highly efficient systems for pulmonary drug delivery. However, they are
Frijlink, H.W., De Boer, A.H.
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Inhalation Performance Analysis of Dry Powder Inhaler
International Journal of Pharmaceuticals, Nutraceuticals and Cosmetic ScienceDry powder inhalers (DPIs) are commonly used to treat respiratory diseases, particularly asthma, lung cancer, and chronic obstructive pulmonary disease, by delivering medications directly to the lungs. This review explores the influence of key formulation parameters such as particle size, morphology, surface roughness, and excipients on the inhalation ...
Muhammad Ikhmal Azhar +2 more
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Inhaled Dry Powder Formulations for Treating Tuberculosis
Current Drug Delivery, 2015Tuberculosis is the second leading cause of death from infectious diseases. Although antitubercular drugs have been traditionally administered orally, there is a growing interest in delivering drugs via the pulmonary route using nebulisers or dry powder inhalers.
Shyamal, Das +2 more
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[Easyhaler--ideal dry powder inhaler].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2010Dry powder inhalers (DPI) differ among each other in many technical aspects, size and value of lung deposition as well as clinical efficacy of inhaled drugs. Easyhaler is a reservoir, multi-dose, high-resistance DPI and it is easy to operate. The device needs low inspiratory flows which are possible to achieve even by asthmatic children over 5-year-old
Emeryk, Andrzej +1 more
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Dry Powder Inhalers (DPI): A Comprehensive Review Article on Dry Powder Inhaler (DPI)
In the treatment of respiratory conditions like asthma and chronic obstructive pulmonary disease (COPD), dry powder inhalers (DPIs) have emerged as a crucial substitute for pressurized metered-dose inhalers (pMDIs). The desire for more effective and user-friendly drug delivery systems, as well as environmental concerns about the chlorofluorocarbon (CFC)openaire +1 more source