Results 51 to 60 of about 1,726,040 (290)
Atmosphere-Ocean Ozone Exchange – A Global Modeling Study of Biogeochemical, Atmospheric and Water-Side Turbulence Dependencies [PDF]
, 2009 The significance of the removal of tropospheric ozone by the oceans, covering ~2/3 of the Earth's surface, has only been addressed in a few studies involving water tank, aircraft, and tower flux measurements.
Helmig, D. +7 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
National Atmospheric Deposition Program 2011 Annual summary [PDF]
, 2012 is peer reviewedSubmitted by Susan Braxton (braxton@illinois.edu) on 2013-01-29T22:55:31Z No. of bitstreams: 1 2011as.pdf: 4443124 bytes, checksum: 1e2ff568a6e350fe41bba46c81de3531 (MD5)Made available in DSpace on 2013-01-29T22:55:31Z (GMT). No.
National Atmospheric Deposition Program
core
Triple oxygen isotopes indicate urbanization affects sources of nitrate in wet and dry atmospheric deposition [PDF]
Atmospheric Chemistry and Physics, 2018 Atmospheric nitrate deposition resulting from anthropogenic activities negatively affects human and environmental health. Identifying deposited nitrate that is produced locally vs.
D. M. Nelson +9 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
National Atmospheric Deposition Program 2010 Annual summary [PDF]
, 2009 At the NADP Fall 2010 Meeting and Scientific Symposium, the NADP voted to approve the Ammonia Monitoring Network (AMoN) as the fifth NADP network.
National Atmospheric Deposition Program
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Tellus: Series B, Chemical and Physical Meteorology, 2013 Due to its significant ecological and climate consequences, atmospheric nitrogen (N) deposition is a growing global concern, especially in the severely N-polluted regions such as the Pearl River Delta (PRD) region of southern China. One-year measurements
Xuemei Wang +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source