Results 61 to 70 of about 1,726,040 (290)

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

open access: yesFEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar   +4 more
wiley   +1 more source

Aporte atmosférico de amônio, nitrato e sulfato em área de floresta ombrófila densa montana na Serra dos Órgãos, RJ Atmospheric deposition of ammonium, nitrate ans sulfate on the montane dense ombrophilous forest in Serra dos Órgãos, RJ

open access: yesQuímica Nova, 2007
Wet and dry (dust) deposition was measured in the Serra dos Órgãos National Park. VWM pH was 5.3. Non-sea-salt (nss) SO4(2-) comprised 97% of total SO4(2-).
Renato de Aragão Ribeiro Rodrigues   +2 more
doaj   +1 more source

Wet and dry deposition of atmospheric nitrogen at ten sites in Northern China [PDF]

open access: yesAtmospheric Chemistry and Physics, 2012
Emissions of reactive nitrogen (N) species can affect surrounding ecosystems via atmospheric deposition. However, few long-term and multi-site measurements have focused on both the wet and the dry deposition of individual N species in large areas of ...
Y. P. Pan, Y. S. Wang, G. Q. Tang, D. Wu
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Importance of dry deposition parameterization choice in global simulations of surface ozone [PDF]

open access: yesAtmospheric Chemistry and Physics, 2019
Dry deposition is a major sink of tropospheric ozone. Increasing evidence has shown that ozone dry deposition actively links meteorology and hydrology with ozone air quality.
A. Y. H. Wong   +4 more
doaj   +1 more source

Assessing Douro Vineyards Exposure to Tropospheric Ozone

open access: yesAtmosphere, 2021
Tropospheric ozone (O3) can strongly damage vegetation. Grapevines (Vitis vinifera L.), in particular, have intermediate sensitivity to ozone. Wine production is an important economic activity, as well as a pillar to the cultural identity of several ...
Ana Ascenso   +10 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Spatial Patterns in Wet and Dry Deposition of Atmospheric Mercury to Illinois Watersheds

open access: yesE3S Web of Conferences, 2013
An intensive one month atmospheric mercury monitoring campaign was carried out at 8 sites in central Illinois, USA, during summer of 2011 to assess spatial patterns in wet and dry deposition.
Lynam M. M., Hall N. L., Dvonch J. T.
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

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