Results 251 to 260 of about 373,290 (326)

Rosemary Essential Oil Microemulsion for Fungal Keratitis Treatment

Chemistry &Biodiversity, EarlyView.
ABSTRACT This study investigated the use of Rosmarinus officinalis (rosemary) essential oil in a microemulsion (ME) formulation for the treatment of ocular fungal keratitis, a serious infection that can lead to blindness. The ME was characterized in terms of pH, stability, homogeneity, osmolarity, and other physicochemical properties.
Saulo Ribeiro, Mariana Coelho Moraes, Denise de Oliveira Scoaris, Jovita Eugênia Gazinelli Cruz Madeira, Silvia Ligório Fialho, Carolina Paula de Souza Moreira   +5 more
wiley   +1 more source

MSC-encapsulated porous microparticle eye drops for autoimmune dry eye disease treatment in NOD mice. [PDF]

Sci Adv
Chen T, Liu R, Chen Q, Feng X, Kong B, Zhao Y.   +5 more
europepmc   +1 more source

Coumarin‐Caged Nanoparticle for Light‐Driven Surface Modification

ChemMedChem, EarlyView.
Photo‐responsive nanoparticles (NPs) enable spatiotemporal control over drug delivery. Attachment of a photo‐labile protecting group (PPG) to cell‐penetrating peptide (CPP) effectively camouflages the positive charge of NPs. Light irradiation cleaves the PPG, exposing the CPP on the NP surface and thereby enhancing cellular uptake.
Jan Birringer, Johannes Konrad, Stephan Melchner, Marius Remmert, Achim Goepferich   +4 more
wiley   +1 more source

Associations of Sleep Duration and Social Jetlag with Dry Eye Disease in Chinese School-Aged Children and Adolescents. [PDF]

Nat Sci Sleep
Luo Y, Gao Y, Guan Z, Liu H, Tao S.
europepmc   +1 more source

The Pathway to Proof‐of‐Concept for BNC210, a Negative Allosteric Modulator of the Alpha‐7 Nicotinic Acetylcholine Receptor (nAChR), for Treatment of Psychiatric Disease

Clinical Pharmacology in Drug Development, EarlyView.
Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan, Elizabeth Doolin, Dharam Paul, Julia Crossman, Michael Odontiadis, Philippe Danjou, Mark Smith, Spyros Papapetropoulos   +7 more
wiley   +1 more source

The Relationship between Dry Eye Disease and Inflammation

, 2016
Tohru Sakimoto
openalex   +2 more sources

Perspective of the Pharmaceuticals and Medical Devices Agency on Drug Development for Childhood Myopia

Clinical Pharmacology &Therapeutics, EarlyView.
Pathologic myopia represents a global public health concern, with increasing prevalence and vision loss risk. Myopia typically develops in childhood and progresses more rapidly with earlier onset. Clinical trials exploring treatments for decelerating myopia progression are underway.
Mitsuru Arima, Motomasa Atsumi, Kumiko Takeuchi, Takumi Aoki, Emi Inagaki, Yosuke Kobayashi, Takuya Kageyama, Kazuki Izumi, Atsushi Yoshimura, Wataru Asakura   +9 more
wiley   +1 more source

Dry Eye Disease: From Causes to Patient Care and Clinical Collaboration-A Narrative Review. [PDF]

Ophthalmol Ther
Aragona P, Barabino S, Di Zazzo A, Giannaccare G, Villani E, Aiello F, Antoniazzi E, Bonini S, Cantera E, Carlini G, Chierego C, Colabelli R, Fasciani R, Franch A, Gabbriellini G, Gagliano CMR, Leonardi A, Macrì A, Mencucci R, Mosca L, Orfeo V, Pinna A, Pocobelli A, Protti R, Rama P, Rania L, Rechichi M, Rubino P, Russo A, Scorcia V, Spadea L, Trentadue M, Troisi S, Versura P, Rolando M.   +34 more
europepmc   +1 more source

Novel liposome-based and in situ gelling artificial tear formulation for dry eye disease treatment

, 2017
Duygu Acar, Irene T. Molina‐Martínez, Miguel Gómez-Ballesteros, M. Guzmán, J.M. Benítez-del-Castillo, Rocı́o Herrero-Vanrell   +5 more
openalex   +2 more sources

Myomaker and Myomixer are required for craniofacial myoblast fusion in zebrafish

Developmental Dynamics, EarlyView.
Abstract Background Craniofacial and trunk skeletal muscles are derived from different progenitor populations during development. Trunk skeletal muscles contain mostly multinucleated myofibers that are formed through myoblast fusion. However, myoblast fusion in craniofacial muscles and its molecular regulation are not well understood.
Zhanxiong Zhang, Pengzheng Yong, Qiaomu Hu, Shaojun Du   +3 more
wiley   +1 more source