Results 121 to 130 of about 1,714,059 (280)
Acta Paediatrica, EarlyView.ABSTRACT Aim This position paper aims to synthesize current evidence on the effects of screen exposure on children's and adolescents' physical, mental and social health, critically review existing international and European guidelines, and propose coordinated, harmonized and age‐appropriate recommendations for policymakers, paediatric societies ...
Lorenza Onorati +6 more
wiley +1 more source
The immunological landscape of the area postrema in neuromyelitis optica spectrum disorders
Brain Pathology, EarlyView.Aquaporin‐4 antibody‐positive neuromyelitis spectrum disorder is characterized by large tissue destructive lesions in medulla, spinal cord, and optic nerves, with only partial recovery from clinical symptoms, and by lesions with very little tissue destruction and mostly complete recovery from clinical symptoms, as seen in the area postrema ...
Qian Yu +11 more
wiley +1 more source
Global Prevalence of Dry Eye Disease in Medical Students: A Systematic Review and Meta-Analysis
VisionDry Eye Disease (DED) is a multifactorial condition increasingly affecting young populations, including medical students, due to intensive screen use, prolonged near work, and demanding academic environments.
Víctor Juan Vera-Ponce +5 more
doaj +1 more source
Etiology, prevalence, and treatment of dry eye disease
, 2009 Johnny L GaytonEyesight Associates, Warner Robins, GA, USAPurpose: This review article examines the prevalence, etiology, and current therapies of dry eye disease, with special focus on postmenopausal women.Method: A systematic literature search ...
Johnny L Gayton
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The potential for biased signalling in the P2Y receptor family of GPCRs
British Journal of Pharmacology, EarlyView.The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk +2 more
wiley +1 more source
Deep Phenotyping in ReNU Syndrome Identifies a Recognizable Age‐Dependent Clinical Trajectory
Clinical Genetics, EarlyView.Longitudinal evaluation of 11 individuals with ReNU syndrome revealed an age‐dependent multisystem trajectory. This longitudinal description may help clinicians anticipate changing needs in feeding, growth, neurological, visual, communication, behavioral, and orthopedic care. ABSTRACT Pathogenic variants in the noncoding gene RNU4‐2 cause ReNU syndrome,
Nadja Pekkola Pacheco +14 more
wiley +1 more source
Annual direct cost of dry eye in Japan
, 2012 Yoshinobu Mizuno, Masakazu Yamada, Chika ShigeyasuDivision for Vision Research, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, JapanOn behalf of The Dry Eye Survey Group, National Hospital Organization of JapanBackground ...
Shigeyasu C, Mizuno Y, Yamada M
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Developmental Medicine &Child Neurology, EarlyView.Abstract Children with neurological impairment (CNI) are at increased risk of malnutrition because of functional, medical, and socioeconomic challenges. However, difficulties in obtaining reliable anthropometric measurements and differences in body composition limit the usefulness of conventional nutritional indicators.
Sarah Vermilyea +19 more
wiley +1 more source
Therapeutic targets in dry eye syndrome.
Drug news & perspectives, 2008 Dry eye is a multifactorial disease of the tears and the ocular surface that manifests with a wide variety of signs and symptoms. It is prevalent in about 33% of the population worldwide. Due to the importance of the pathology, new tests, drugs and technologies have been developed to assist the diagnosis, management and follow-up of the disease ...
Peral Cerda, María Asunción +3 more
openaire +2 more sources
Charting the course of Sjögren's disease: A historical analysis of scientific progress
European Journal of Oral Sciences, EarlyView.Abstract Sjögren's disease (SjD) bears the name of the Swedish ophthalmologist Henrik Sjögren. His 1933 doctoral thesis on keratoconjunctivitis sicca ignited interest, yet much remains under debate. SjD is an autoimmune disorder that primarily affects the exocrine glands, particularly the salivary and lacrimal glands, leading to a dryness of the eyes ...
Diego Ustárroz Cantali +3 more
wiley +1 more source