Results 201 to 210 of about 1,645,367 (305)

Contact Lens-Associated Ocular Surface and Corneal Disorders. [PDF]

Methods Protoc
Abdelaziz O, Ghalibafan S, Ruiz-Lozano RE, Peterson JC, Gallo RA, Djalilian AR.   +5 more
europepmc   +1 more source

Psilocybin, From Ancestral Use to Therapeutic Potential: A Multidimensional Review of Its Pharmacological Basis and Current Perspectives

Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 5, September 2026.
ABSTRACT Objective This review critically examines psilocybin, with particular emphasis on its pharmacokinetics and pharmacodynamics, including its serotonergic, neuroplastic, and anti‐inflammatory mechanisms. It integrates historical context, preclinical and clinical evidence, and evaluates emerging therapeutic potential, safety, microdosing practices,
José Norberto Vásquez‐Bonilla
wiley   +1 more source

Study protocol for a randomised controlled trial to evaluate the prophylactic efficacy of combined intense pulsed light (IPL) and low-level light therapy (LLLT) in preventing laser corneal refractive surgery-induced dry eye: the Treat Eye Before Laser induced Dry (TEBeLiD) study. [PDF]

BMJ Open
Kerkouri S, Garcin T, Cochener B.
europepmc   +1 more source

The Clinical Utility of Labial Gland Biopsy in Patients With Suspected Neuro‐Sjögren

Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
ABSTRACT Background Neuro‐Sjögren, the neurological subtype of Sjögren's Disease (SjD), is difficult to diagnose due to its heterogeneity and diverse manifestations. While the diagnostic role of labial gland biopsy (LGB) in SjD is established, its significance in Neuro‐Sjögren remains unclear.
Zhen Tian, Xuemei Li, Xia Li, Yajie Wang, Chunxiu Wang, Yi Zhao   +5 more
wiley   +1 more source

Eyes of Fibromyalgia. [PDF]

Biomedicines
Yavaş AD, Şaipi A, Akçay S.
europepmc   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, Volume 3, Issue 3, September 2026.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

Effectiveness of a heparin-like glycosaminoglycan from snail mucus in a murine model of dry eye. [PDF]

J Transl Med
Ou S, Zhang L, Lin L, Zhang L, Jiang H, Long Q, Zhang M, Zheng X, Tian X, Wu Y, Wu M, Gu H.   +11 more
europepmc   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Integrated management of dry eye-depression comorbidity: mechanistic insights and temporal therapeutic strategies. [PDF]

Front Med (Lausanne)
Yang TD, Wu CL, Li XJ, Hu SR, Zang J.
europepmc   +1 more source

Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou, Xuemei Ren, Yingjie Ren, Ruiping Wu, Ruiman Geng, Le Chen, Zhuo Li   +6 more
wiley   +1 more source