Results 71 to 80 of about 108,243 (386)

cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression

Advanced Science, EarlyView.
cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang, Yu Deng, Jianfeng Chen, Quentin Hahn, David S. Umbaugh, Zhigang Zhang, Yanqiong Zhang, Sarah E. Rowe, Lupeng Li, Laura E. Herring, Brian P. Conlon, Edward A. Miao, Blossom Damania, Anna Mae Diehl, Pengda Liu   +14 more
wiley   +1 more source

Dry Eye Following Cataract Surgery in Women Over 50 Years Old

پزشکی بالینی ابن سینا, 2016
Introduction: Dry eye is a common problem amongst post-menopausal women. Cataract surgery may worsen symptoms of dry eye and this can influence the quality of life in patients.
Nooshin Bazzazi, Fatemeh Eslami, Pouyan Pahlavani, Siamak Akbarzadeh   +3 more
doaj  

Salivary Gland Sonography in Patients with Primary Fibromyalgia—A Pilot Study

Life
Primary Sjogren’s syndrome (pSS) is often concomitant with fibromyalgia (FM). Salivary gland sonography aids in the diagnosis of pSS. We aimed to discover, in primary FM patients, the presence of pSS in undiagnosed patients through salivary gland ...
Ching-Tsai Lin, Der-Yuan Chen, Yi-Hsing Chen, Chien-Chen Lai, Kuo-Tung Tang   +4 more
doaj   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

Platelet-rich plasma in diabetic dry eye disease

Revista Brasileira de Oftalmologia
Objective: To evaluate the effectiveness of autologous Plasma- rich platelet (PRP) in symptomatic dry eye of diabetic patients. Design A prospective single group interventional study.
Marina Viegas Moura Rezende Ribeiro, Fabiano Timbó Barbosa, Luiz Eduardo Feliciano Ribeiro, Celina Maria Costa Lacet, João Marcelo de Almeida Gusmão Lyra, Verônica de Lima Guedes, Patrícia Costa Alves Pinto, Eurica Adélia Nogueira Ribeiro   +7 more
doaj   +1 more source

Diadenosine polyphosphates in the tears of aniridia patients [PDF]

, 2015
Purpose To quantify diadenosine polyphosphate levels in tears of congenital aniridia patients to estimate the ocular surface changes associated with congenital aniridia compared to normal individuals. Methods Fifteen patients diagnosed with congenital
Carracedo Rodríguez, Juan Gonzalo, Peral Cerdá, Assumpta, Pintor, Jesús   +2 more
core   +1 more source

Hormone Replacement Therapy and Dry Eye Syndrome [PDF]

JAMA, 2001
Postmenopausal hormone replacement therapy (HRT) use is common in the United States. Some research suggests that estrogen may have detrimental effects on the tear film and could influence the development of dry eye syndrome, but few data are available on this relationship.To determine the relationship of HRT and dry eye syndrome.The Women's Health ...
Schaumberg, Debra A., Buring, Julie, Sullivan, David, Dana, Reza   +3 more
openaire   +5 more sources

Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined

Aggregate, EarlyView.
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei, Xikai Wang, Zhuang Hu, Jierui Yan, Xiaobo Wang, Haoran Wang, Ya Hou, Pengfei Zhang, Qihang Ding   +8 more
wiley   +1 more source

Characteristics of respondents with glaucoma and dry eye in a national panel survey

Clinical Ophthalmology, 2009
Jordana K Schmier1, David W Covert21Exponent Inc., Alexandria, VA, USA; 2Alcon Research, Ltd., Fort Worth, TX, USABackground: There is an increasing body of evidence strongly suggesting that glaucoma medications may contribute to ocular surface disease ...
Jordana K Schmier, David W Covert
doaj  

Different concentrations of hyaluronic acid eye drops for dry eye syndrome: a systematic review and Meta-analysis [PDF]

International Journal of Ophthalmology
AIM: To compare high or low concentration of hyaluronic acid eye drops (HY) for dry eye syndromes (DES). METHODS: Randomized controlled trials (RCTs) comparing various concentrations of HY were searched in PubMed, Embase, Web of Science, Cochrane ...
Xiao-Wei Ouyang, Sheng Fang, Yun-Min Yi, Shi-Peng Zou, Qi-Yu Hu, Zi-Xuan Huang, Qing-Xia Li, Jin-Yan Luo   +7 more
doaj   +1 more source