Results 71 to 80 of about 97,702 (295)

Platelet-rich plasma in diabetic dry eye disease

Revista Brasileira de Oftalmologia
Objective: To evaluate the effectiveness of autologous Plasma- rich platelet (PRP) in symptomatic dry eye of diabetic patients. Design A prospective single group interventional study.
Marina Viegas Moura Rezende Ribeiro, Fabiano Timbó Barbosa, Luiz Eduardo Feliciano Ribeiro, Celina Maria Costa Lacet, João Marcelo de Almeida Gusmão Lyra, Verônica de Lima Guedes, Patrícia Costa Alves Pinto, Eurica Adélia Nogueira Ribeiro   +7 more
doaj   +1 more source

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell, E. C. Ward, L. R. Wishart, R. Perera, C. Barrett, K. A. Edmiston, E. Mitchell, A. Pigott, R. Pitt, K. Russell, B. A. Chan, R. Ladwa   +11 more
wiley   +1 more source

Diagnosis and Treatment of Ocular Pain: the Ophthalmologist’s Perspective

Current Ophthalmology Reports, 2017
Purpose of ReviewThe aim of this review is to help ophthalmologists and other clinicians understand and treat ocular neuropathic pain.Recent FindingsAdvances in the field of neurophysiology of ocular sensations explain why some cases of dry eye may ...
D. Jacobs
semanticscholar   +1 more source

Punctal occlusion for dry eye syndrome

Cochrane Database of Systematic Reviews, 2017
Dry eye syndrome is a disorder of the tear film that is associated with symptoms of ocular discomfort. Punctal occlusion is a mechanical treatment that blocks the tear drainage system in order to aid in the preservation of natural tears on the ocular surface.To assess the effects of punctal plugs versus no punctal plugs, different types of punctal ...
Ann-Margret, Ervin, Andrew, Law, Andrew D, Pucker   +2 more
openaire   +3 more sources

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, EarlyView.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Influence of eyelid pigmentation on the diagnosis of meibomian gland dysfunction

Clinical Ophthalmology, 2019
Max J Blumberg,1 Amy E Millen,2 Sangita P Patel1,3 1Department of Ophthalmology, Ross Eye Institute, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY, USA; 2Department of Epidemiology and ...
Blumberg MJ, Millen AE, Patel SP
doaj  

Efficacy of hyaluronic acid and butyroyl glutathione in the management of glaucoma-related ocular surface disease: a prospective, interventional, double-blind, cross-over post market study

Frontiers in Pharmacology
IntroductionTo evaluate the efficacy of a novel eye drop formulation containing hyaluronic acid (0.2%) and butyroyl-glutathione (GSHC4, 0.4%) in glaucoma-associated ocular surface disease (G-OSD), and to explore putative mechanisms of action through in ...
Gabriele Gallo Afflitto, Gabriele Gallo Afflitto, Marialaura Fanelli, Vita Petrone, Rossella Chirico, Francesca Ceccarelli, Alessio Martucci, Antonella Minutolo, Francesco Aiello, Enrico Garaci, Claudia Matteucci, Carlo Nucci   +11 more
doaj   +1 more source

The tear film and ocular mucins

Veterinary Ophthalmology, 2004
The trilaminar tear film, composed of the lipid, aqueous and mucin layers, has many functions including defending the ocular surface. The aqueous layer has several soluble antimicrobial factors that protect the ocular surface. Ocular mucins have recently
H. Davidson, V. Kuonen
semanticscholar   +1 more source