Results 41 to 50 of about 6,312,799 (286)

Incidence and Control of Mastitis During the Dry Period

open access: yesJournal of Dairy Science, 1974
Abstract In a trial involving 402 cows, neomycin sulfate (500mg) was infused into all quarters of alternate cows (810 quarters) on the day of drying off. The remaining cows received neomycin only in quarters with clinical mastitis during the last month of lactation or on the day of drying off (31 quarters). Teats on one side of all cows were dipped in
G E, Ward, L H, Schultz
openaire   +2 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Comparison of performance and metabolism from late pregnancy to early lactation in dairy cows with elevated v. normal body condition at dry-off

open access: yesAnimal, 2019
Excessive mobilization of body reserves during the transition from pregnancy to lactation imposes a risk for metabolic diseases on dairy cows. We aimed to establish an experimental model for high v.
K. Schuh   +10 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Genetic Evaluation of some Productive and Days Open Traits in a Commercial Friesian Herd in Egypt Using Different Animal Models [PDF]

open access: yesJournal of Animal and Poultry Production, 2018
Estimates of covariance component and some  genetic parameters were evaluated by using multi traits animal models, for Total milk yield (TMY),Lactation length (LL) ) ,Dry period (DP)  and Days open(DO).
M. Mostafa   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Effects of bovine casein hydrolysate as a dry cow therapy on prevention and cure of bovine intramammary infection, milk production, and somatic cell count in the subsequent lactation

open access: yesJournal of Dairy Science, 2022
: The primary objectives were to investigate the efficacy of bovine casein hydrolysate (bCNH) as a dry cow therapy at (1) preventing new intramammary infection (IMI) postpartum of all bacteria and coagulase-negative staphylococci (CNS), and (2) curing ...
Ezra Shoshani, M. van Straten
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

A retrospective study on the relationship among different dry period lengths, udder health status and their possible effects on the reproductive performance of Holstein-Frisian cows [PDF]

open access: yesJournal of Veterinary Medical Research, 2019
This study aimed to evaluate the effect of different dry period lnghts (DPLs) on the udder health and fertility during the subsequent lactation. The impact of subclinical mastitis (SCM) and clinical mastitis (CM) on the reproductive efficiency were also ...
Abdeltawab A.Y. Khalil   +1 more
doaj   +1 more source

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