Results 71 to 80 of about 6,312,799 (286)

Tropical dry forest recovery : processes and causes of change [PDF]

open access: yes, 2009
Seasonally dry areas are one of the preferred zones for human inhabitance in the tropics. Large forest areas are converted to other land uses and many are covered by secondary forests that grow naturally after cessation of disturbance.
Lebrija Trejos, E.E.
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Dry periods influence the ecohydrology of the rainforest

open access: yes, 2021
Climate change and deforestation influence the rainfall patterns in the tropics, thereby increasing the risk of drought-induced forest-to-savanna transitions. Forest ecosystems respond to these changing environmental conditions by adapting various drought coping strategies driven by different magnitudes of water-stress (i.e., defined
Chandrakant Singh   +4 more
openaire   +1 more source

Factors Affecting the Milk Production Traits and Lactation Curve of the Indigenous River Buffalo Populations in Bangladesh

open access: yesAnimals
Household buffalo dairy farming is gaining popularity nowadays in Bangladesh because of the outstanding food value of buffalo milk as well as the lower production cost of buffalo compared to cattle.
Abdullah Ibne Omar   +9 more
doaj   +1 more source

Heat Stress Impacts Immune Status in Cows Across the Life Cycle

open access: yesFrontiers in Veterinary Science, 2020
Heat stress has a myriad of effects on dairy cattle across the life cycle. Whereas, the most commonly recognized impacts are associated with production responses, emerging evidence indicates that heat stress profoundly alters the immune response of ...
Geoffrey E. Dahl   +2 more
doaj   +1 more source

Differential expression of ABC transporters and their regulatory genes during lactation and dry period in bovine mammary tissue [PDF]

open access: yes, 2008
ATP-binding cassette (ABC) transporters play a pivotal role in human physiology, and mutations in these genes often result in severe hereditary diseases.
Farke, Carolin   +3 more
core   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

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