Pulmonary delivery of insulin by dry powder inhaler formulations [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Insulin therapy is critical in diabetic patients for controlling blood glucose levels. In recent years, pulmonary insulin delivery has emerged as an alternative approach for overcoming the therapeutic disadvantages of subcutaneous insulin ...
Mohsen Imenshahidi +6 more
doaj +4 more sources
Simultaneous Spray Drying for Combination Dry Powder Inhaler Formulations [PDF]
Pharmaceutics, 2022 Spray drying is a particle engineering technique used to manufacture respirable pharmaceutical powders that are suitable for delivery to the deep lung. It is amenable to processing both small molecules and biologic actives, including proteins.
Kimberly B. Shepard +2 more
doaj +4 more sources
Pulmonary Circulation, 2021 Relative to healthy subjects, patients with pulmonary arterial hypertension often present with decreased respiratory muscle strength, resulting in decreased maximum inspiratory pressure.
Sandeep Sahay +5 more
doaj +2 more sources
Optimization of Carrier-Based Dry Powder Inhaler Performance: A Review [PDF]
PharmaceuticsDry powder inhalers (DPI’s) are becoming increasingly popular due to growing interest in pulmonary drug delivery and their performance is the net result of a series of processes carried out during the formulation development and manufacturing process ...
Tanu Mehta +4 more
doaj +2 more sources
Dry powder inhalation, part 1: ancient history and precursors to modern dry powder inhalers
Expert Opinion on Drug Delivery, 2022 Inhalation of herbs and other compounds has a long history but habits for medical treatment are intertwined with rituals to obtain hallucinatory effects and pleasurable sensations. Several examples of inhaled herbs, and the diseases they were used for, based on early translations of ancient manuscripts related to inhalation were found to be speculative
Anne H. de Boer +2 more
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Pressurized Metered-Dose Inhaler Versus Dry Powder Inhaler Adherence Among Individuals with Asthma and COPD [PDF]
Advances in Respiratory MedicineBackground: The core management of most individuals with asthma and COPD is daily treatment with inhalers such as inhaled corticosteroids (ICS) and long-acting bronchodilators.
Dekel Shlomi +5 more
doaj +2 more sources
Successful Use of Easyhaler® Dry Powder Inhaler in Patients with Chronic Obstructive Pulmonary Disease; Analysis of Peak Inspiratory Flow from Three Clinical Trials [PDF]
Pulmonary TherapyIntroduction There is increasing pressure to use environmentally friendly dry powder inhalers (DPI) instead of pressurized metered-dose inhalers (pMDI).
Annette Kainu +6 more
doaj +2 more sources
In Vitro Drug Delivery of a Fixed-Dose Combination of Fluticasone Furoate/Umeclidinium/Vilanterol from a Dry Powder Inhaler. [PDF]
J Aerosol Med Pulm Drug Deliv, 2023 Hamilton M +5 more
europepmc +2 more sources
KONA Powder and Particle Journal, 2013 This paper reviews scientific understandings relevant to the dry powder inhaler (DPI) development including turbulent airflow characteristics in the inhaler, microparticle entrainment and deaggregation within the airflow and device.
Zhen Xu, Anthony J Hickey
doaj +3 more sources
Usability and Robustness of the Wixela Inhub Dry Powder Inhaler. [PDF]
J Aerosol Med Pulm Drug Deliv, 2021 Allan R +6 more
europepmc +2 more sources