Results 91 to 100 of about 16,216 (335)

Investigating the relationship between peak inspiratory flow rate and volume of inhalation from a Diskus™ Inhaler and baseline spirometric parameters: a cross-sectional study [PDF]

, 2014
Drug delivery from a Dry Powder Inhaler (DPI) is dependent on the peak inspiratory flow rate (PIFR) generated. Currently available methods for estimating PIFR from most DPIs are limited and mainly rely on subjective assessment.
Al Bannai, Hasan, Bholah, Tariq, Costello, Richard W, Costello, Simon, Seheult, Jansen N, Sulaiman, Imran, Tee, Kee Chun   +6 more
core   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

Assessment of Patient’s Inhalation Technique in Songklanagarind Hospital: Proportion of Correct Inhaler Technique and Influenced Factors

Journal of Health Science and Medical Research (JHSMR), 2012
Objective: To determine the proportion and influenced factors related to the correct inhaler technique of patients in Songklanagarind Hospital. Material and Methods: This study was prospective observation and cross-sectional analysis study. The technique
Warangkana Keeratichananont, Kittisak Thangsattayatisathan   +1 more
doaj  

Inhaler Competence and Patient Satisfaction with Easyhaler: Results of Two Real-Life Multicentre Studies in Asthma and COPD. [PDF]

, 2013
OBJECTIVE: The aim of this study was to investigate patients' inhaler competence and satisfaction with the Easyhaler(R) dry powder inhaler. DESIGN: Two open, uncontrolled, non-randomised studies.
Gabriella Gálffy, Gyula Németh, Györgyi Mezei, Lilla Tamási, Marta Orosz, Olof Selroos, Veronika Müller   +6 more
core   +2 more sources

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

Advanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu, Zhongcheng Li, Qian Ren, Ziqian Lu, Yubing Zhang, Yili Guo, Ruomeng Li, Die Hu, Linglin Zhang   +8 more
wiley   +1 more source

Preparation and Characterization of Celecoxib Agglomerated Nanocrystals and Dry Powder Inhalation Formulations to Improve its Aerosolization Performance

Pharmaceutical Sciences, 2017
Background: Celecoxib is a non-steroidal anti-inflammatory drug used extensively in the treatment of pain, arthritis, and cancers. However, its administration is limited due to its several disadvantages including gastric irritation and hepatic first pass
Sepideh Mardani 1, Maryam Maghsoodi 2 * , Saeed Ghanbarzadeh 3,4, Ali Nokhodchi 5, Shadi Yaqoubi 6, Hamed Hamishehkar 7 *
doaj   +1 more source

Pharmaceutical equivalence of the combination formulation of budesonide and formoterol in a single capsule with a dry powder inhaler [PDF]

, 2012
OBJECTIVE: To evaluate the pharmaceutical equivalence of a test formulation (fixed-dose combination of budesonide and formoterol fumarate in a single capsule dispensed in an Aerocaps® inhaler) in relation to a reference formulation (budesonide and ...
Andrade-lima, Marina, Fernandes, Ana Luisa Godoy [UNIFESP], Pereira, Luiz Fernando Ferreira   +2 more
core   +3 more sources

Dry powder inhalation, part 2

Expert Opinion on Drug Delivery, 2022
Introduction: The manufacture of modern dry powder inhalers (DPIs), starting with the Spinhaler (Fisons) in 1967, was only possible thanks to a series of technological developments in the 20th century, of which many started first around 1950. Not until then, it became possible to design and develop effective, cheap and mass-produced DPIs.
de Boer, Anne Haaije, Hagedoorn, Paul, Grasmeijer, Floris   +2 more
openaire   +1 more source

Injectable Chondroitin Sulfate Methacrylate Hydrogel Microspheres Co‐Loaded with GLPM Nanozyme, Dexamethasone, and Stem Cells for Synergistic Osteoarthritis Therapy

Advanced Science, EarlyView.
A multifunctional injectable microsphere system is fabricated via UV‐assisted microfluidic cross‐linking, integrating nanozyme‐based ROS scavenging, sustained dexamethasone release, and stem cell delivery. Upon IA injection, the microspheres adapt to joint stress, suppress inflammation, and promote cartilage regeneration, offering a minimally invasive ...
Xiaochen Feng, Ying Fang, Hongwei Yu, Yicheng Wang, Yunze Xu, Chunxiao Shi, Haike Xia, Ranjith Kumar Kankala, Aizheng Chen, Shibin Wang, Chaoping Fu   +10 more
wiley   +1 more source

ADVANCEMENTS IN DRY POWDER INHALER

Asian Journal of Pharmaceutical and Clinical Research, 2017
The dry powder inhaler (DPI) has become widely known as a very attractive platform for drug delivery. DPIs are being used for the treatment of asthma and chronic obstructive pulmonary disease by many patients. There are over 20 devices presently in the DPI market. DPIs are preferred over nebulizers and pressurized metered dose inhalers.
Ganga Srinivasan, Advait Shetty
openaire   +2 more sources