Results 101 to 110 of about 16,216 (335)

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

Advanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo, Wenda Zhong, Huishuang Zhao, Yueying An, Xinyu Dong, Zhengbo Li, Shuangfeng Qin, Guangzhao Xu, Xiangguo Yue, Xudong Wang, Wen Sun, Zhe‐Sheng Chen, Weiguo Song, Liuya Wei, Fahui Li   +14 more
wiley   +1 more source

Prospective Evaluation of Exacerbations Associated with Suboptimal Peak Inspiratory Flow Among Stable Outpatients with COPD

International Journal of COPD, 2022
Donald A Mahler,1 Xiaoli Niu,2 Kathleen L Deering,3 Carole Dembek2 1Geisel School of Medicine, Dartmouth, Hanover, NH, USA and Valley Regional Hospital, Claremont, NH, USA; 2Sunovion Pharmaceuticals Inc., Marlborough, MA, USA; 3EPI-Q, Inc, Oak Brook, IL,
Mahler DA, Niu X, Deering KL, Dembek C
doaj  

A Critical Review on Emerging Trends in Dry Powder Inhaler Formulation for the Treatment of Pulmonary Aspergillosis [PDF]

, 2020
Shen Nam Cheng, Zhi Guang Tan, Manisha Pandey, Teerapol Srichana, Mallikarjuna Rao Pichika, Bapi Gorain, Hira Choudhury   +6 more
openalex   +1 more source

Long-acting beta2-agonists for chronic obstructive pulmonary disease. [PDF]

, 2013
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a respiratory disease that causes progressive symptoms of breathlessness, cough and mucus build-up.
Aalbers, Allegra, Amgott, Anderson, Appleton, Arievich, Bateman, Bateman, Baumgartner, Beeh, Berger, Bleecker, Bleecker, Bogdan, Bogdan, Boyd, Boyd, Briggs, British Medical Association and the Royal Pharmaceutical Society of Great Britain, Brusasco, Brusasco, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Campbell, Campbell, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Celli, Chapman, Chapman, Cheyne, Chong, Chong, Corhay, Dahl, Dahl, Dahl, Dahl, Dahl, Dahl, Dal Negro, Dal Negro, Doherty, Doherty, Doherty, Doherty, Donohue, Donohue, Donohue, Donohue, Effing, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Geake, Greefhorst, Greefhorst, Greefhorst, Gross, Hanania, Hanania, Hanrahan, Hanrahan, Hanrahan, Hanrahan, Hanrahan, Higgins, Hogan, Horstman, Hunjan, Hunjan, Hutchinson, Jenkins, Jenkins, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Jones, Karner, Karner, Karner, Karner, Karner, Keene, Kerwin, Kerwin, Khamis, Kliber, Kornmann, Kornmann, Kristufek, Kristufek, Kristufek, Lacasse, Laties, Littner, Lofdahl, Lofdahl, Lofdahl, Lofdahl, Mahler, Mahler, Mahler, Mahler, Matiz-Bueno, Matiz-Bueno, McDonough, McGarvey, Meer, Nannini, Nannini, Nannini, Nelson, Nelson, Nelson, Nelson, Nitschmann, Noord, Noord, Puhan, Qaseem, Rennard, Rennard, Rennard, Rennard, Rodrigo, Rossi, Rutten-van Molken, Rutten-van Mölken, Sacchetta, Sciurba, Song, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Stahl, Steffensen, Steffensen, Stockley, Stockley, Szafranski, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Tashkin, Vestbo, Vestbo, Vestbo, Vestbo, Vogelmeier, Vogelmeier, Wadbo, Wang, Watkins, Welsh, Yang   +198 more
core   +1 more source

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

Advanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye, Jianfeng Xiang, Siqi Zhou, Qintao Ge, Aihetaimujiang Anwaier, Kun Chang, Gang Wei, Jiahe Lu, Xi Tian, Shuxuan Zhu, Yuchen Jiang, Wei Zhang, Tingting Cai, Moran Xu, Dingwei Ye, Danfeng Xu, Tao Wang, Hailiang Zhang, Wenhao Xu   +18 more
wiley   +1 more source

Knowledge and practice of dry powder inhalation among patients with chronic obstructive pulmonary disease in a regional hospital, Nepal

International Journal of General Medicine, 2018
Mira Adhikari Baral Department of Nursing, Pokhara Campus, Tribhuvan University, Institute of Medicine, Pokhara, Nepal Purpose: Dry powder inhalation is a cornerstone of treatment in patients with COPD.
Baral MA
doaj  

The combination of fluticasone furoate and vilanterol trifenatate in the management of asthma: clinical trial evidence and experience

Therapeutic Advances in Respiratory Disease, 2016
The treatment of persistent asthma has been aided by the recent approval of new medications. The combined inhaled corticosteroid (ICS)/long-acting β2 agonist (LABA) powder inhaler fluticasone furoate (FF)/vilanterol trifenatate (VI) is one of these new ...
Timothy E. Albertson, John R. Richards, Amir A. Zeki   +2 more
doaj   +1 more source

Easyhaler®: an overview of an inhaler device for day-to-day use in patients with asthma and chronic obstructive pulmonary disease

Drugs in Context, 2019
Inhalation therapy is likely to continue to dominate asthma and chronic obstructive pulmonary disease (COPD) treatment. The pressurised metered-dose inhaler (pMDI) accounts for most of the global inhaler market, but this kind of device is difficult to ...
Federico Lavorini
doaj   +1 more source

Factors associated with health status and exacerbations in COPD maintenance therapy with dry powder inhalers [PDF]

, 2022
Janwillem Kocks, Hans Wouters, Sinthia Bosnic‐Anticevich, Joyce van Cooten, Jaime Correia de Sousa, Biljana Cvetkovski, Richard Dekhuijzen, Lars Dijk, Evgeni Dvortsin, Marina García Pardo, Asparuh Gardev, Radosław Gawlik, Iris van Geer - Postmus, Iris van der Ham, Marten Harbers, Alberto de la Hoz, Ymke Janse, Marjan Kerkhof, Federico Lavorini, Tiago Maricoto, Jiska Meijer, Boyd Metz, David Price, Miguel Román-Rodríguez, Kirsten Schuttel, Nilouq Stoker, Ioanna Tsiligianni, Omar S. Usmani, Marika T. Leving   +28 more
openalex   +1 more source

Does size really matter:relationship of particle size to lung deposition and exhaled fraction [PDF]

, 2017
We demonstrate that extra-fine particles are not associated with an appreciably higher exhaled fraction, hence explaining their efficacy profile in asthma.
Brian Lipworth, De Backer, Gianluigi Poli, Hauber, Jabbal, Kraft, Lipworth, Manoharan, Manoharan, Nicolini, Sunny Jabbal, Usmani, Usmani   +12 more
core   +2 more sources