Results 21 to 30 of about 16,216 (335)

Novel Approaches for the Treatment of Pulmonary Tuberculosis

Pharmaceutics, 2020
Tuberculosis (TB) is a contagious airborne disease caused by Mycobacterium tuberculosis, which primarily affects human lungs. The progression of drug-susceptible TB to drug-resistant strains, MDR-TB and XDR-TB, has become worldwide challenge in ...
Zhi Ming Tan, Gui Ping Lai, Manisha Pandey, Teerapol Srichana, Mallikarjuna Rao Pichika, Bapi Gorain, Subrat Kumar Bhattamishra, Hira Choudhury   +7 more
doaj   +1 more source

Comparison of serious inhaler technique errors made by device-naïve patients using three different dry powder inhalers: a randomised, crossover, open-label study [PDF]

, 2016
Background: Serious inhaler technique errors can impair drug delivery to the lungs. This randomised, crossover, open-label study evaluated the proportion of patients making predefined serious errors with Pulmojet compared with Diskus and Turbohaler dry ...
A Palander, A Papi, Anne Burden, AS Melani, BL Laube, Catherine Hutton, D Price, D Price, D Price, D Price, David B. Price, Dawn Shan, E Mehuys, Erika Sims, F Lavorini, F Yildiz, Federico Lavorini, GK Crompton, GN Rootmensen, H Al-Jahdali, H Chrystyn, Henry Chrystyn, IA Basheti, J Haughney, J Haughney, J Palen van der, J Steier, JC McElnay, JC Virchow, JL Rau, John Efthimiou, John Haughney, KG Nielsen, L Borgstrom, M Molimard, M Molimard, M Moller, M Schulte, MA Crane, Mathieu Molimard, MS Blaiss, Nicolas Roche, PN Dekhuijzen, RA Al-Showair, S Verver, Sinthia Bosnic-Anticevich, SP Newman, SZ Bosnic-Anticevich, V Giraud, V Giraud, V Giraud, W Azouz, Y Aydemir   +52 more
core   +2 more sources

Influence of excipients on spray-dried powders for inhalation [PDF]

, 2014
Two areas attracting considerable attention when developing effective pulmonary drug delivery systems include the improvement of aerosolisation efficiency of the inhaled formulation and the controlled release of drug from the formulation following ...
Adi, Azarmi, Begat, Chan, Chew, Chew, Conti, Corrigan, Coucke, Derom, Edwards, Ely, En-Yu Xu, Farid, Glover, Gray, Griesenbach, Hao-Ying Li, Hooton, Jalalipour, Jing Guo, Kamiya, Kobayashi, Learoyd, Learoyd, Li, Li, Li, Li, Li, Mishra, Momeni, Parsons, Patton, Peter C. Seville, Prakash Rao, Seville, Seville, Sham, Sinn, Sou, Sou, Ståhl, Vergote, Ying Xu, Zeng   +45 more
core   +1 more source

Inhalable spray-dried chondroitin sulphate microparticles: effect of different solvents on particle properties and drug activity [PDF]

, 2020
Spray-drying stands as one of the most used techniques to produce inhalable microparticles, but several parameters from both the process and the used materials affect the properties of the resulting microparticles.
Buttini, Francesca, da Costa, Ana M Rosa, Faleiro, Maria Leonor, Flórez Fernández, Noelia, Grenha, Ana, Rodrigues, Susana, Torres, María Dolores   +6 more
core   +1 more source

Dry powder inhalation: past, present and future [PDF]

Expert Opinion on Drug Delivery, 2016
Early dry powder inhalers (DPIs) were designed for low drug doses in asthma and COPD therapy. Nearly all concepts contained carrier-based formulations and lacked efficient dispersion principles. Therefore, particle engineering and powder processing are increasingly applied to achieve acceptable lung deposition with these poorly designed inhalers. Areas
De Boer, A. H, Hagedoorn, P, Hoppentocht, M, Grasmeijer, F, Frijlink, H. W., BUTTINI, Francesca   +5 more
openaire   +3 more sources

Switching patients from other inhaled corticosteroid devices to the Easyhaler(®) : historical, matched-cohort study of real-life asthma patients [PDF]

, 2014
Peer reviewedPublisher ...
Gould, Shuna, Hutton, Catherine, King, Christine, Price, David, Thomas, Vicky, von Ziegenweidt, Julie   +5 more
core   +1 more source

Salbutamol powder inhaled from the Diskhaler compared to salbutamol as nebulizer solution in severe chronic airways obstruction [PDF]

, 1995
The bronchodilatory effect of four doses of salbutamol powder (1·6 mg) from a multi-dose dry powder inhaler, the Diskhaler, was compared to the effect of 2·5 ml salbutamol nebulizer solution (1 mg ml−1) from a jet nebulizer, Pari Inhalierboy, in a ...
Buijs, Pascal, Koopmans, Marion, Kuiken, Thijs, van Amerongen, Geert, van den Hoogen, Bernadette, van Run, Peter   +5 more
core   +7 more sources

Exploring the role of quantitative feedback in inhaler technique education : a cluster-randomised, two-arm, parallel-group, repeated-measures study [PDF]

, 2014
Peer reviewedPublisher ...
Amin Basheti, Iman, Bosnic-Anticevich, Sinthia, Price, David, Toumas-Shehata, Mariam   +3 more
core   +2 more sources

Impact of the number of repeated inhalations and patient characteristics on the residual amount of inhaled laninamivir octanoate hydrate dry powder in pediatric patients with influenza

Journal of Pharmaceutical Health Care and Sciences, 2017
Background A dry powder inhaled formulation is used for the anti-influenza drug laninamivir octanoate hydrate (laninamivir). Although two successive inhalations (puffs) are recommended to minimize residual amounts of active ingredients, previous reports ...
Toshiki Murasaka, Kenji Ikemura, Tomoyuki Enokiya, Yuichi Muraki, Mayumi Ikemura, Koji Terada, Takuya Iwamoto, Masahiro Okuda   +7 more
doaj   +1 more source

Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children [PDF]

, 2008
BackgroundCombination therapies are frequently recommended as maintenance therapy for people with asthma, whose disease is not adequately controlled with inhaled steroids.
Aalbers, Aalbers, Aalbers, Aalbers, Adachi, Adams, Adams, Alonso, Ambrose, Becker, Bleecker, Bleecker, Bleecker, Bleecker, Bousquet, Bousquet, Bousquet, Brambilla, Buhl, Cates, Cates, Cazzola, Chuchalin, Creemers, D'Urzo, Dahl, Dahl, Dahl, Edwards, Fitzgerald, FitzGerald, Gibson, Greenstone, Hampel, Hampel Jr, Higgins, Higgins, Jenkins, Jenkins, Johansson, Kaik, Kuna, Lee, Lee, Lee, Lundback, Lötvall, Martin, Miller, Molimard, Ni Chroinin, Noord, O'Connor, Palmqvist, Palmqvist, Price, Price, Price, Ringdal, Ringdal, Suissa, Vogelmeier, Walters, Welte, Williams   +64 more
core   +1 more source