PLoS MedicineBackgroundFluticasone-salmeterol is available in both metered-dose and dry powder inhaler formulations for the treatment of chronic obstructive pulmonary disease (COPD).
Brandon J Demkowicz +4 more
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Patient considerations in the treatment of COPD: focus on the new combination inhaler umeclidinium/vilanterol. [PDF]
, 2015 Medication adherence among patients with chronic diseases, such as COPD, may be suboptimal, and many factors contribute to this poor adherence. One major factor is the frequency of medication dosing.
Albertson, Timothy E +3 more
core +1 more source
São Paulo Medical Journal, 2001 CONTEXT: Budesonide is an inhaled corticosteroid with high topical potency and low systemic activity recommended in the treatment of chronic asthma. OBJECTIVE: This study was conducted to determine the efficacy and safety of inhaled budesonide via a ...
Ana Luisa Godoy Fernandes +5 more
doaj +1 more source
Formulation pre-screening of inhalation powders using computational atom-atom systematic search method [PDF]
, 2014 This is an open access article published under a Creative Commons Attribution (CC-BY) License, which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.The synthonic modeling approach provides ...
Collins, Elizabeth +10 more
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Biopolymeric Inhalable Dry Powders for Pulmonary Drug Delivery
PharmaceuticalsNatural and synthetic biopolymers are gaining popularity in the development of inhaled drug formulations. Their highly tunable properties and ability to sustain drug release allow for the incorporation of attributes not achieved in dry powder inhaler ...
Sara E. Maloney Norcross +3 more
doaj +1 more source
A Method to Calculate Adherence to Inhaled Therapy That Reflects the Changes in Clinical Features of Asthma. [PDF]
, 2016 Rationale Currently studies on adherence to inhaled medications report Average Adherence over time. This measure does not account for variations in the interval between doses nor for errors in inhaler use.
Boland, Fiona +12 more
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Factors associated with appropriate inhaler use in patients with COPD - lessons from the REAL survey [PDF]
, 2018 The authors thank Clarice Field (PhD) and Paul McKiernan (PhD) of Novartis for providing medical writing support, which was funded by Novartis AG, Basel, Switzerland, in accordance with Good Publication Practice (GPP3) guidelines (http://www.ismpp.org ...
Gasser, Matthias +5 more
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Biophysical model to predict lung delivery from a dual bronchodilator dry-powder inhaler
International Journal of Pharmaceutics: X, 2019 A biophysical lung model was designed to predict inhaled drug deposition in patients with obstructive airway disease, and quantitatively investigate sources of deposition variability. Different mouth-throat anatomies at varying simulated inhalation flows
Myrna B. Dolovich +3 more
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The Inhalation Characteristics of Patients When They Use Different Dry Powder Inhalers [PDF]
, 2015 Background: The characteristics of each inhalation maneuver when patients use dry powder inhalers (DPIs) are important, because they control the quality of the emitted dose.
Alaboud A +8 more
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Identification of Inhaler Technique Errors Among Asthmatic Patients
Zanco Journal of Pure and Applied Sciences, 2023 Proper inhaler technique is a fundamental problem that directly relates to asthma control. Adequate inhaler administration is influenced by a variety of factors, including patient- and device-related factors.
Brwa Omer Sharif +2 more
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