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Manifesto on small airway involvement and management in asthma and chronic obstructive pulmonary disease: an Interasma (Global Asthma Association - GAA) and World Allergy Organization (WAO) document endorsed by Allergic Rhinitis and its Impact on Asthma (ARIA) and Global Allergy and Asthma European Network (GA2LEN) [PDF]

, 2016
Evidence that enables us to identify, assess, and access the small airways in asthma and chronic obstructive pulmonary disease (COPD) has led INTERASMA (Global Asthma Association) and WAO to take a position on the role of the small airways in these ...
A. Cruz, A. Fink-Wagner, A. Yanez, A. Yorgancioglu, ARIA, C. Baez Loyola, C. Nunes, D. Deleanu, D. Ryan, E. Hossny, F. Braido, F. Lavorini, F. Levi-Schaffer, for Interasma Executive Board, G. Passalacqua, G. Rodrigo, G. Walter Canonica, GA2LEN, H. Saito, I. J. Ansotegui, J. A. Ortega-Martell, J. Berstein, J. Bousquet, J. C. Ivancevich, J. Celedon, K. Dobashi, K. Ohta, L. Caraballo, L. Dubuske, L. J. Rosenwasser, L. P. Boulet, L. Zhang, M. Akdis, M. Ebisawa, M. Sanchez-Borges, M. Tang, M. Zernotti, N. Scichilone, O. S. Usmani, P. Greenberger, P. Vichyanond, R. Mosges, R. Pawankar, S. Benjaponpitak, S. Bonini, S. Fineman, S. N. Gonzalez-Diaz, S. Nakajima, T. Slavyanskaya, T. Zuberbier, W. Burks, Z. Awad El-Sayed   +51 more
core   +14 more sources

Inhaled budesonide for adults with mild-to-moderate asthma: a randomized placebo-controlled, double-blind clinical trial

São Paulo Medical Journal, 2001
CONTEXT: Budesonide is an inhaled corticosteroid with high topical potency and low systemic activity recommended in the treatment of chronic asthma. OBJECTIVE: This study was conducted to determine the efficacy and safety of inhaled budesonide via a ...
Ana Luisa Godoy Fernandes, Sonia Maria Faresin, Maria Marta Amorim, Carlos Cézar Fritscher, Carlos Alberto de Castro Pereira, José Roberto Jardim   +5 more
doaj   +1 more source

Recent advances in capsule-based dry powder inhaler technology

Multidisciplinary Respiratory Medicine, 2017
Pulmonary drug delivery is currently the focus of accelerated research and development because of the potential to produce maximum therapeutic benefit to patients by directly targeting drug to the site of pathology in the lungs.
Federico Lavorini, Massimo Pistolesi, Omar S. Usmani   +2 more
doaj   +1 more source

Patient considerations in the treatment of COPD: focus on the new combination inhaler umeclidinium/vilanterol. [PDF]

, 2015
Medication adherence among patients with chronic diseases, such as COPD, may be suboptimal, and many factors contribute to this poor adherence. One major factor is the frequency of medication dosing.
Albertson, Timothy E, Harper, Richart, Murin, Susan, Sandrock, Christian   +3 more
core   +1 more source

Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease. [PDF]

, 2014
BACKGROUND: Inhaled corticosteroids (ICS) are anti-inflammatory drugs that have proven benefits for people with worsening symptoms of chronic obstructive pulmonary disease (COPD) and repeated exacerbations.
Agarwal, Allegra, Anderson, Anzueto, Bale, Blais, Bleecker, Bourbeau, Bourbeau, Briggs, Briggs, Briggs, British Thoracic Society, Burge, Burge, Burge, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Calverley, Cates, Celli, Celli, Celli, Celli, Celli, Celli, Chavannes, Choudhury, Choudhury, Cipriani, Corhay, D'Urzo, Dahl, Dal Negro, Dalal, DiSantostefano, Dransfield, Drummond, Effing, Egede, Ernst, Ferguson, Ferguson, Ferguson, Ferguson, Ferguson, Gizycki, Glenny, Grunsven, Grunsven, Halpin, Hanania, Hanania, Hanania, Hattotuwa, Horstman, Hunjan, Hunjan, Jarad, Jebrak, Jenkins, Jenkins, Johnell, Johnson, Jones, Jones, Jones, Jones, Jones, Jones, Kardos, Kardos, Keene, Korsgaard, Lacasse, Lange, Lapperre, Laptseva, Lofdahl, Lofdahl, Lofdahl, Lofdahl, Lofdahl, Lung Health Study Research Group, Mahler, Mahler, Marchand, Martinez, McDonough, McGarvey, Meer, Milanowski, Mirici, Monninkhof, Nannini, Nannini, Nitschmann, Ozol, Paggiaro, Partridge, Pauwels, Pauwels, Pauwels, Puhan, Renkema, Rennard, Roberts, Rossios, Sacchetta, Schermer, Senderovitz, Shaker, Shaker, Sharafkhaneh, Sharafkhaneh, Sin, Singanayagam, Singh, Song, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Spencer, Suissa, Szafranski, Tashkin, Valk, Valk, Verhoeven, Verhoeven, Verhoeven, Vestbo, Vestbo, Vestbo, Vestbo, Vestbo, Vestbo, Vestbo, Weir, Wouters, Wouters, Yang, Yildiz   +163 more
core   +1 more source

Inactivating SARS‐CoV‐2 Virus with MOF‐Composites as Smart Face Masks

Advanced Functional Materials, EarlyView.
In situ preparation and functionalization of MOF@Cotton fabrics as smart face masks for the immobilization of proteins and inactivation viruses, such as SARS‐CoV‐2. Abstract The significant impact of the SARS‐CoV‐2 (COVID‐19) pandemic outbreak on people's lives has highlighted the urgent need for effective personal protective equipment.
Romy Ettlinger, Aamod V. Desai, Hau Lam Jody Cheong, Louise L. Major, Terry K. Smith, Aaron B. Naden, Jane Hilton, Catherine S. Adamson, A. Robert Armstrong, Russell E. Morris   +9 more
wiley   +1 more source

The comparative effectiveness and safety of fluticasone-salmeterol via metered-dose versus dry powder inhalers for COPD: A new user cohort study.

PLoS Medicine
BackgroundFluticasone-salmeterol is available in both metered-dose and dry powder inhaler formulations for the treatment of chronic obstructive pulmonary disease (COPD).
Brandon J Demkowicz, Kevin Rader, Shirley V Wang, Aaron S Kesselheim, William B Feldman   +4 more
doaj   +1 more source

Potential of a cyclone prototype spacer to improve in vitro dry powder delivery [PDF]

, 2013
Copyright The Author(s) 2013. This article is published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium ...
A Nair, A Voss, AJ Hickey, AR Clark, C Terzano, CG Thiel, D Ganderton, Darragh Murnane, DI Daniher, Digby D. Symons, EA Matida, F Lavorini, F Lavorini, H Bisgaard, H Bisgaard, H Bisgaard, H Chrystyn, Irene Parisini, JP Mitchell, K Demirkan, K Svartengren, L Borgstrom, L Borgström, LI Harrison, M Hindle, MEAC Broeders, ML Everard, N Islam, P Begat, PW Barry, R Buhl, R Pauwels, RAM Al-Showair, Sean J. Cheng, SP Newman, T Ehtezazi, T Srichana, T Srichana, WES Kamin, WH DeHaan, WY Tarsin, XM Zeng   +41 more
core   +2 more sources

4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles

Advanced Functional Materials, EarlyView.
Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner, Francesco Carraro, Behnaz Abbasgholi‐NA, Simone Dal Zilio, Max Schmallegger, Helmar Wiltsche, Lingcong Ge, Michael R. Reithofer, Efwita Astria, Laura Villanova, Heinz Amenitsch, Christian Doonan, Paolo Falcaro   +12 more
wiley   +1 more source

Assessment of inhalational techniques and their common errors in bronchial asthma patients coming to tertiary hospital of South Gujarat

Indian Journal of Respiratory Care, 2020
Objective: The objective was to assess the inhalational techniques and its common errors in bronchial asthma patients. Methodology: This cross-sectional study was conducted from July 2019 to September 2019. All known asthmatic patients on inhaler therapy
Shivani Dalal, Khyati Shamaliya, Anas Patni   +2 more
doaj   +1 more source