Results 71 to 80 of about 16,216 (335)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Most frequent errors in inhalation technique of patients with asthma treated at a tertiary care hospital

Einstein (São Paulo)
Objective: To demonstrate the most frequent errors in inhalation technique in patients with asthma undergoing treatment at a tertiary care hospital. Methods: A cross-sectional study with a convenience sample of asthma patients aged 18 years or over ...
Carlos Leonardo Carvalho Pessôa, Maria Julia da Silva Mattos, Artur Renato Moura Alho, Marianna Martini Fischmann, Bruno Mendes Haerdy, Ana Carolina Castro Côrtes, Flávio de Oliveira Mendes, Sandra Mara Silva Brignol   +7 more
doaj   +1 more source

Errors in Aerosol Inhaler Use and Their Effects on Maternal and Fetal Outcomes among Pregnant Asthmatic Women (Subanalysis from QAKCOP Study)

Canadian Respiratory Journal, 2018
Data on inhaler technique and its effects on maternal and fetal outcomes during pregnancy are seldom reported. The primary objective of this study was to evaluate inhaler technique and identify errors in inhaler use among pregnant women with asthma ...
Wanis H. Ibrahim, Fatima Rasul, Mushtaq Ahmad, Abeer S. Bajwa, Laith I. Alamlih, Anam M. El Arabi, Dhabia Al-Mohannadi, Mohammed Y. Siddiqui, Israa S. Al-Sheikh, Azdin A. Ibrahim   +9 more
doaj   +1 more source

Multivariate data analysis to assess dry powder inhalers performance from powder properties [PDF]

, 2016
The study aimed at investigating the correlations among the physical and bulk properties of carrier based dry powder inhaler formulations and the performance of the powder inhaler device estimated by in-vitro tests for a specific active pharmaceutical ...
Bosi, Roberto, Cafiero, Claudio, COCCHI, Marina, Cottini, Ciro, Elia, Andrea, Lutero, Emilio, Riolo, Daniela   +6 more
core   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

Advanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan, Bence Bajusz, Norbert Fabók, Marina Rudan Dimlic, Jelena Budimir, Tshepang Mqatywa, Miklós Gyöngy, Márton Ferencz, Dorottya Kocsis, Olexandr Bondarenko, Mariia Rolduhina, Milena Lengyel, Istvan Antal, Rebecca Hengsbach, Franciska Erdő, Amir Fahmi   +15 more
wiley   +1 more source

INHALATION THERAPY IN CHILDREN: ISSUES AND OPTIONS

Вопросы современной педиатрии, 2014
Today inhalation therapy forms the basis of treatment for children and adults with bronchial asthma. In the current market there is a great number of various drug delivery systems, such as: nebulisers, pressurised metered-dose inhalers and dry powder ...
L. R. Selimzyanova, E. А. Promyslova, E. А. Vishnyeva   +2 more
doaj   +1 more source

Cardiac safety of tiotropium in patients with cardiac events: a retrospective analysis of the UPLIFT® trial. [PDF]

, 2015
BackgroundTiotropium is an anticholinergic bronchodilator for symptom relief and reducing exacerbations with an established safety profile in patients with chronic obstructive pulmonary disease (COPD).
Decramer, Marc, Leimer, Inge, Metzdorf, Norbert, Tashkin, Donald P   +3 more
core   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

Characterization of a Human Powered Nebulizer Compressor for Resource Poor Settings [PDF]

, 2014
Background Respiratory disease accounts for three of the ten leading causes of death worldwide. Many of these diseases can be treated and diagnosed using a nebulizer. Nebulizers can also be used to safely and efficiently deliver vaccines.
Hallberg, Christopher J., Kopesky, William K., Lysaught, Mary Therese, Olson, Lars E., Zmudka, Christopher E.   +4 more
core   +2 more sources

Injectable Stimuli‐Responsive Amphiphilic Hydrogel for Rapid Hemostasis, Robust Tissue Adhesion, and Controlled Drug Delivery in Trauma and Surgical Care

Advanced Healthcare Materials, EarlyView.
Fast‐acting hydrogel seals bleeding wounds as the illustrated injectable, pH‐responsive network rapidly gels in situ to stop hemorrhage, adhere strongly to wet tissue, and release antibiotics in a controlled, pH‐dependent manner. The material withstands high pressures, shows excellent biocompatibility, and degrades safely, offering a versatile platform
Arvind K. Singh Chandel, Runali Patil, Abrar Ali Khan, Deeksha Pandit, Kaushik Chatterjee, Maurice N. Collins   +5 more
wiley   +1 more source