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Development of Dry Powder Inhalers
Recent Patents on Drug Delivery & Formulation, 2007Development of dry powder inhalers involves powder recrystallization, formulation, dispersion, delivery, and deposition of the therapeutic agent in different regions of the airways in prophylaxis/ treatment/ diagnosis of pulmonary and systemic disorders.
Mahavir B, Chougule +3 more
openaire +2 more sources
2021
Dry powder inhalers (DPIs) are the latest development in inhaled drug therapy. They deliver the drug as a dry powder in a suitable formulation which can be drug only, or contain excipients, and has excellent stability compared to drug solutions or suspensions.
de Boer, Anne, Thalberg, Kyrre
openaire +1 more source
Dry powder inhalers (DPIs) are the latest development in inhaled drug therapy. They deliver the drug as a dry powder in a suitable formulation which can be drug only, or contain excipients, and has excellent stability compared to drug solutions or suspensions.
de Boer, Anne, Thalberg, Kyrre
openaire +1 more source
Advanced Drug Delivery Reviews, 1997
The search for alternatives to metered-dose inhalers has accelerated recently in a bid to find effective products that do not use chlorofluorocarbon (CFC) propellants. This paper reviews the factors to be considered in developing dry powder inhalers (DPIs), particularly the formulation, metering design and flow path in the device.
, Sumby, , Slater, , Atkins, , Prime
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The search for alternatives to metered-dose inhalers has accelerated recently in a bid to find effective products that do not use chlorofluorocarbon (CFC) propellants. This paper reviews the factors to be considered in developing dry powder inhalers (DPIs), particularly the formulation, metering design and flow path in the device.
, Sumby, , Slater, , Atkins, , Prime
openaire +2 more sources
2019
Recent history of dry powder inhalation dates back to the sixties of the previous century. The design and development of dry powder inhalers (DPIs) in this period was driven by patient dissatisfaction with metered dose inhaler (MDI) use and the imminent ban of chlorofluorocarbon propellants in these MDIs. For their design, the 1960s state of the art in
Anne H. de Boer, Floris Grasmeijer
openaire +1 more source
Recent history of dry powder inhalation dates back to the sixties of the previous century. The design and development of dry powder inhalers (DPIs) in this period was driven by patient dissatisfaction with metered dose inhaler (MDI) use and the imminent ban of chlorofluorocarbon propellants in these MDIs. For their design, the 1960s state of the art in
Anne H. de Boer, Floris Grasmeijer
openaire +1 more source
Journal of Cell Science & Therapy, 2017
Dry powder inhaler (DPI) is a vehicle that is used to transfer drug into body. The efficient delivery of drug into the lungs depends on performance of drug delivery system and powder formulation. DPI and drug chemistry needs to fulfill safety, efficacy, bio-equivalence and reliability for product approval.
Daud Faran Asif +5 more
openaire +1 more source
Dry powder inhaler (DPI) is a vehicle that is used to transfer drug into body. The efficient delivery of drug into the lungs depends on performance of drug delivery system and powder formulation. DPI and drug chemistry needs to fulfill safety, efficacy, bio-equivalence and reliability for product approval.
Daud Faran Asif +5 more
openaire +1 more source
Pulmonary Delivery of Inhalable Nanoparticles: Dry Powder Inhalers
Therapeutic Delivery, 2011Pulmonary administration of inhalable nanoparticles (NPs) is an emerging area of interest. Dry powder inhalers may offer particular advantages for pulmonary administration of NPs. This article reviews research performed on the formulation of inhalable NPs as dry powder to achieve deep-lung deposition and enhance NP redispersibility.
M H D Kamal, Al-Hallak +5 more
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Formulation Considerations for Dry Powder Inhalers
Therapeutic Delivery, 2014The market for inhalable dry powder medication has consistently grown over past years. Targeting the lungs has been recognized to offer several advantages compared with oral application of drugs. The successive development of inhalation products has led to advances in local treatment of different respiratory diseases, but has also demonstrated the ...
Eike, Cordts, Hartwig, Steckel
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Developing Dry Powder Inhaler Formulations
Journal of Aerosol Medicine and Pulmonary Drug DeliveryThis section aims to provide a concise and contemporary technical perspective and reference resource covering dry powder inhaler (DPI) formulations. While DPI products are currently the leading inhaled products in terms of sales value, a number of confounding perspectives are presented to illustrate why they are considered surprisingly, and often ...
David A V, Morton, David, Barling
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Dry Powder Inhalers: From Bench to Bedside
Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2023Dry powder inhalers (DPIs) are now widely prescribed and preferred by the majority of patients. These devices have many advantages over the traditional pressurized metered-dose inhaler (pMDI) but they do have disadvantages. The characteristics of the dose emitted from a DPI are affected by the inhalation manoeuvre used by a patient.
Henry, Chrystyn +2 more
openaire +2 more sources
2016
Pulmonary tract is one of the oldest routes used for administration of drugs. During the past decade, the lung has been very attractive for achieving systemic and local absorption of various drugs, particularly for those drugs that exhibit poor bioavailability when administered by the oral or parenteral route.
Aysu Yurdasiper +3 more
openaire +1 more source
Pulmonary tract is one of the oldest routes used for administration of drugs. During the past decade, the lung has been very attractive for achieving systemic and local absorption of various drugs, particularly for those drugs that exhibit poor bioavailability when administered by the oral or parenteral route.
Aysu Yurdasiper +3 more
openaire +1 more source