Dry powder inhalation, part 1: ancient history and precursors to modern dry powder inhalers
Inhalation of herbs and other compounds has a long history but habits for medical treatment are intertwined with rituals to obtain hallucinatory effects and pleasurable sensations. Several examples of inhaled herbs, and the diseases they were used for, based on early translations of ancient manuscripts related to inhalation were found to be speculative
Anne Haaije de Boer +2 more
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Asthma and chronic obstructive pulmonary disease (COPD) are common chronic respiratory diseases characterized by an inflammatory process that extends from the central to peripheral airways.
Ashfaq Hasan +4 more
doaj +1 more source
Switching patients from other inhaled corticosteroid devices to the Easyhaler(®) : historical, matched-cohort study of real-life asthma patients [PDF]
Peer reviewedPublisher ...
Gould, Shuna +5 more
core +1 more source
Dry powder inhalation: past, present and future [PDF]
Early dry powder inhalers (DPIs) were designed for low drug doses in asthma and COPD therapy. Nearly all concepts contained carrier-based formulations and lacked efficient dispersion principles. Therefore, particle engineering and powder processing are increasingly applied to achieve acceptable lung deposition with these poorly designed inhalers. Areas
De Boer, A. H +5 more
openaire +3 more sources
Inhalation characteristics of asthma patients, COPD patients and healthy volunteers with the Spiromax® and Turbuhaler® devices: a randomised, cross-over study. [PDF]
BACKGROUND: Spiromax® is a novel dry-powder inhaler containing formulations of budesonide plus formoterol (BF). The device is intended to provide dose equivalence with enhanced user-friendliness compared to BF Turbuhaler® in asthma and chronic ...
A Hardwell +30 more
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Comparison of serious inhaler technique errors made by device-naïve patients using three different dry powder inhalers: a randomised, crossover, open-label study [PDF]
Background: Serious inhaler technique errors can impair drug delivery to the lungs. This randomised, crossover, open-label study evaluated the proportion of patients making predefined serious errors with Pulmojet compared with Diskus and Turbohaler dry ...
A Palander +52 more
core +2 more sources
Challenges Associated with the Pulmonary Delivery of Therapeutic Dry Powders for Preclinical Testing
Significant progress has been made over the last half-century in delivering therapeutics by the pulmonary route. Inhaled therapeutics are administered to humans using metered-dose inhalers, nebulizers, or dry powder inhalers, and each device requires a ...
Dominique N. Price +2 more
doaj +1 more source
Patients with asthma and Chronic Obstructive Respiratory Disease (COPD) rely on three main device classes for inhalation therapy: metered-dose inhalers (MDIs), dry powder inhalers (DPIs) and soft-mist inhalers (SMIs).
Sara Panigone +5 more
doaj +1 more source
Nanoparticles in the treatment of chronic lung diseases [PDF]
Nanoparticles, although considered a topic of modern medicine, actually have an interesting history. Currently, advances in nanomedicine hold great promise as drug carrier systems for sustained release and targeted delivery of diverse therapeutic agents.
Alexescu, Teodora G +9 more
core +2 more sources
Inhalacijska terapija jedan je od stupova liječenja plućnih bolesti. Na dostavu lijeka u pluća utječu anatomija dišnog sustava, fizikalno-kemijska svojstva samog lijeka te čimbenici prijenosa lijeka (sredstva za dostavljanje lijeka, tehnika disanja i ...
Ivan Bambir +4 more
doaj +1 more source

