CONTEXT AND OBJECTIVE: Treatment of asthma implies inhalation of specific drugs to reach high concentrations in the respiratory tree and ensure low drug bioavailability and few adverse effects.
Carlos Leonardo Carvalho Pessôa +7 more
doaj +1 more source
Potential of a cyclone prototype spacer to improve in vitro dry powder delivery [PDF]
Copyright The Author(s) 2013. This article is published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium ...
A Nair +41 more
core +2 more sources
The Inhalation Characteristics of Patients When They Use Different Dry Powder Inhalers [PDF]
Background: The characteristics of each inhalation maneuver when patients use dry powder inhalers (DPIs) are important, because they control the quality of the emitted dose.
Alaboud A +8 more
core +1 more source
Inhalation therapy using small-interfering RNA (siRNA) is a potentially effective therapeutic strategy for lung cancer because of its high gene-silencing effects and sequence specificity.
Kei Miwata +13 more
doaj +1 more source
Patient considerations in the treatment of COPD: focus on the new combination inhaler umeclidinium/vilanterol. [PDF]
Medication adherence among patients with chronic diseases, such as COPD, may be suboptimal, and many factors contribute to this poor adherence. One major factor is the frequency of medication dosing.
Albertson, Timothy E +3 more
core +1 more source
Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children [PDF]
BackgroundCombination therapies are frequently recommended as maintenance therapy for people with asthma, whose disease is not adequately controlled with inhaled steroids.
Aalbers +64 more
core +1 more source
The clinical effectiveness and cost-effectiveness of inhaler devices used in the routine management of chronic asthma in older children: a systematic review and economic evaluation [PDF]
Background: This review examines the clinical effectiveness and cost-effectiveness of hand-held inhalers to deliver medication for the routine management of chronic asthma in children aged between 5 and 15 years.
Beverley, C. +4 more
core +1 more source
Inhalation technique assessment and evaluation for the need of pharmaceutical intervention in respiratory pathologies patients [PDF]
Objective: To evaluate rate and type of errors in inhalation technique of patients seen in hospitals at the observation area in the emergency department, as well as patients seen in the outpatients clinic at the primary care pharmaceutical consultation,
Paloma Castellano-Copa +2 more
doaj +1 more source
Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events [PDF]
Background An increase in serious adverse events with both regular formoterol and regular salmeterol in chronic asthma has been demonstrated in comparison with placebo in previous Cochrane reviews.
Aalbers +27 more
core +2 more sources
Dispersion and Characterization of Pharmaceutical Dry Powder Aerosols
Dry powder inhalers may be employed for the delivery of drugs to the lungs for the treatment of pulmonary and systemic diseases. Dry powder inhalers consist of a formulation, metering system and delivery device.
Craig A. Dunber +2 more
doaj +1 more source

