Results 31 to 40 of about 9,904 (185)

Intratracheal Administration of siRNA Dry Powder Targeting Vascular Endothelial Growth Factor Inhibits Lung Tumor Growth in Mice

Molecular Therapy: Nucleic Acids, 2018
Inhalation therapy using small-interfering RNA (siRNA) is a potentially effective therapeutic strategy for lung cancer because of its high gene-silencing effects and sequence specificity.
Kei Miwata, Hirokazu Okamoto, Taku Nakashima, Daisuke Ihara, Yasushi Horimasu, Takeshi Masuda, Shintaro Miyamoto, Hiroshi Iwamoto, Kazunori Fujitaka, Hironobu Hamada, Ayumi Shibata, Takaaki Ito, Tomoyuki Okuda, Noboru Hattori   +13 more
doaj   +1 more source

Combination fluticasone and salmeterol versus fixed dose combination budesonide and formoterol for chronic asthma in adults and children [PDF]

, 2008
BackgroundCombination therapies are frequently recommended as maintenance therapy for people with asthma, whose disease is not adequately controlled with inhaled steroids.
Aalbers, Aalbers, Aalbers, Aalbers, Adachi, Adams, Adams, Alonso, Ambrose, Becker, Bleecker, Bleecker, Bleecker, Bleecker, Bousquet, Bousquet, Bousquet, Brambilla, Buhl, Cates, Cates, Cazzola, Chuchalin, Creemers, D'Urzo, Dahl, Dahl, Dahl, Edwards, Fitzgerald, FitzGerald, Gibson, Greenstone, Hampel, Hampel Jr, Higgins, Higgins, Jenkins, Jenkins, Johansson, Kaik, Kuna, Lee, Lee, Lee, Lundback, Lötvall, Martin, Miller, Molimard, Ni Chroinin, Noord, O'Connor, Palmqvist, Palmqvist, Price, Price, Price, Ringdal, Ringdal, Suissa, Vogelmeier, Walters, Welte, Williams   +64 more
core   +1 more source

Patient considerations in the treatment of COPD: focus on the new combination inhaler umeclidinium/vilanterol. [PDF]

, 2015
Medication adherence among patients with chronic diseases, such as COPD, may be suboptimal, and many factors contribute to this poor adherence. One major factor is the frequency of medication dosing.
Albertson, Timothy E, Harper, Richart, Murin, Susan, Sandrock, Christian   +3 more
core   +1 more source

How to match the optimal currently available inhaler device to an individual child with asthma or recurrent wheeze [PDF]

, 2015
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in ...
Dekhuijzen, Richard, Gappa, Monika, Garcia-Marcos, Luis, Lenney, Warren, Pedersen, Søren, Price, David, van Aalderen, Wim M   +6 more
core   +5 more sources

The clinical effectiveness and cost-effectiveness of inhaler devices used in the routine management of chronic asthma in older children: a systematic review and economic evaluation [PDF]

, 2002
Background: This review examines the clinical effectiveness and cost-effectiveness of hand-held inhalers to deliver medication for the routine management of chronic asthma in children aged between 5 and 15 years.
Beverley, C., Lim, J.N.W., Peters, J., Smith, S., Stevenson, M.   +4 more
core   +1 more source

Factors associated with appropriate inhaler use in patients with COPD - lessons from the REAL survey [PDF]

, 2018
The authors thank Clarice Field (PhD) and Paul McKiernan (PhD) of Novartis for providing medical writing support, which was funded by Novartis AG, Basel, Switzerland, in accordance with Good Publication Practice (GPP3) guidelines (http://www.ismpp.org ...
Gasser, Matthias, Gutzwiller, Florian S, Keininger, Dorothy L, Price, David, Viswanad, Boomi, Walda, Susann   +5 more
core   +1 more source

Dispersion and Characterization of Pharmaceutical Dry Powder Aerosols

KONA Powder and Particle Journal, 2014
Dry powder inhalers may be employed for the delivery of drugs to the lungs for the treatment of pulmonary and systemic diseases. Dry powder inhalers consist of a formulation, metering system and delivery device.
Craig A. Dunber, Anthony J. Hickey, Peter Holzner   +2 more
doaj   +1 more source

Inhalation technique assessment and evaluation for the need of pharmaceutical intervention in respiratory pathologies patients [PDF]

Farmacia Hospitalaria, 2019
Objective: To evaluate rate and type of errors in inhalation technique of patients seen in hospitals at the observation area in the emergency department, as well as patients seen in the outpatients clinic at the primary care pharmaceutical consultation,
Paloma Castellano-Copa, Jaime Gulín-Dávila, Yveth Michelle Tajes-González   +2 more
doaj   +1 more source

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an inhaled corticosteroid for chronic asthma: serious adverse events [PDF]

, 2010
Background An increase in serious adverse events with both regular formoterol and regular salmeterol in chronic asthma has been demonstrated in comparison with placebo in previous Cochrane reviews.
Aalbers, Aalbers, Altman, Barnes, Beach, Bleecker, Busse, Cates, Cates, Cates, Cates, Cates, Dahl, Ducharme, Ducharme, Ducharme, Giembycz, Higgins, Lasserson, Lipworth, Nelson, Ni Chroinin, Papi, Ringdal, Salpeter, Tamminen, Walters, Walters   +27 more
core   +2 more sources

Evaluating Patient Preferences of Maintenance Therapy for the Treatment of Chronic Obstructive Pulmonary Disease: A Discrete Choice Experiment in the UK, USA and Germany. [PDF]

, 2020
Introduction: With increasing availability of different treatments for chronic obstructive pulmonary disease (COPD), we sought to understand patient preferences for COPD treatment in the UK, USA, and Germany using a discrete choice experiment (DCE ...
Doll, HA, Gunsoy, NB, Ismaila, AS, Janssen, EM, Jones, PW, Lewis, HB, Llewellyn, S, Schroeder, M   +7 more
core   +1 more source